transmembrane domains

Peter Ashton pda2 at york.ac.uk
Mon Mar 30 15:15:25 EST 1998


I'm not sure about 2 or 8 TM domains, but a lot of the immune system markers
have got 4 (which is at least an even number). Examples would be CD81, CD82
and CD151.

Pete Ashton
University of York, UK

Simon Hoffenberg wrote in message <6fhfl6$t07 at gazette.bcm.tmc.edu>...
>Dear netters,
>
>If there is more than 1 transmembrane domain in a protein, what are the
>combinations? For example, 7 domains in receptors coupled to G-proteins or
>12 in adenylate cyclase. Is it possible to have 2 or 8-9 domains? If these
>numbers are not allowed by Mother Nature, does it mean that these proteins
>are in fact 1 and 7 transmembrane domain proteins, respectively?
>
>Simon Hoffenberg
>Baylor College of Medicine
>Houston, TX
>simonh at bcm.tmc.edu





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