?Why alkaline pH in protein refold?

Clive dennison at unpsun1.cc.unp.ac.za
Mon Oct 19 11:58:49 EST 1998


Disulfide exchange is promoted at higher pH because of the connection
between redox potential and pH
----------
>From: g3937506 at STUDENT1.MAHIDOL.AC.TH (Jongrak Kittiworakarn)
In article <3624020E.C612EAA5 at student.mahidol.ac.th>,
g3937506 at STUDENT1.MAHIDOL.AC.TH (Jongrak Kittiworakarn) wrote:


>Dear all:
>
>Is it neccessary to refold a protein in alkaline pH?
>Does this prevent any chemical modification ?
>Thanks for all suggestion.
>
>Jongrak
>
>--
>-----------------------------------Mr. Jongrak Kittiworakarn
>                                   g3937506 at student.mahidol.ac.th
>
>     Inst. of Science and Technology for Research and Development
>     Mahidol University (Salaya Campus)
>     Salaya, Nokornprathom, THAILAND.
>     Tel. 001-66-2-441-9003-7 ext.1277,1278,1279
>     Fax. 001-66-2-441-9906, 001-66-2-441-1013
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