Freeze-drying

Reno T. Nguyen reno at cbl.umces.edu
Fri Aug 13 10:22:06 EST 1999


On Fri, 13 Aug 1999, KuS wrote:

> Hello,
> 
> I would just like to know if the principles of the freeze-drying in a
> lyophilizator and in a speed-vac machine are the same?
> 
> Thanks,
> 
> Barbara (info at kos-computers.si)


Hi Barbara,

Well, although both freeze-drying (lyophilization) and speed-vac drying
involve pulling a vacuum on your samples, the process of removal of water
in each instrument is different.  With freeze-drying, the samples are
frozen, and water is removed through the process of sublimation- solid
water is lost as a gas.  With a speed-vac, the sample is not frozen but is
usually heated in a chamber while being spun at high rpm's; liquid water
is lost as a gas.

Reno

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Reno T. Nguyen
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