Postdoc position: Polycomb-group-dependent transcriptional silencing

[Rick Jones]

Postdoctoral position to study Polycomb-group-dependent transcriptional 
silencing

An NIH-funded postdoctoral position is available immediately to study the
molecular/biochemical mechanisms by which Drosophila Polycomb-group (PcG)
proteins maintain the transcriptional silence of target genes.  To date, at
least three multimeric PcG protein complexes have been identified.  However,
little is known about the biochemical activities of these complexes and the
mechanisms by which they alter chromatin structure and maintain
transcriptional silence of target genes.  Current and future projects in our
lab include purification and characterization of protein complexes that
contain the PcG protein Enhancer of zeste [E(z)], and to initiate functional
analysis of the components of these complexes.  More information and a list
of recent publications from our lab is available at the following web page:
http://www.smu.edu/~biology/jones.html.

Individuals with expertise in protein biochemistry, chromatin protein
analysis, and/or molecular biology are encouraged to send an application,
including a C.V. and the names and addresses of three referees, to:

Dr. Richard Jones, Dept. of Biological Sciences, Southern Methodist
University, Dallas, TX 75275-0376.  email: rjones at mail.smu.edu
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