Data base searches

baltim baltim1 at home.com
Thu Nov 9 19:18:08 EST 2000


On Thu, 09 Nov 2000 15:35:33 -0800, Tim Myles
<tmyles at leland.stanford.edu> wrote:

>Hello All,
>
>I have an interesting problem.  I have been trying (unsuccessfully) to
>try and search the prtoein data base for any human extracellular
>proteins that contain either C-terminal Arginines or Lysines.  We are
>looking for proteins that are potential substrates for
>carboxypeptidases.  As far as i know, there is no defined for consesus
>sequence recognised by carboxypeptidases.
>
>I look forward to any help!.
>
>Tim
>

I assume you are using a standard BLAST program available at such
places as NCBI. If so then beware that you will need to turn filtering
off if your looking for strings of repeated residues. Otherwise they
will be masked and overlooked.








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