SDS-PAGE of low pI proteins

Kristina Warton K.Warton at
Sun Dec 23 01:19:00 EST 2001

Is anyone aware of published work showing that proteins with very low
isoelectric points migrate aberrantly slowly on SDS-PAGE? I think it may be
because they bind less SDS and end up with a lower overall negative charge.
I've seen this glossed over in a paper, but I haven't been able to find any
methods papers where this is specifically looked at.



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