Predicting *basic* protein structure
khatipovNO at NOuchicago.edu
Thu Aug 8 17:25:04 EST 2002
I think tools at expasy.ch (www.expasy.ch/tools) can help predict some
structural features (helices, loops, strands). Check Agadir, PredictProtein,
etc. I myself have a program that is currently being developed by one of my
colleagues, which can predict folding of small proteins by basically
randomly changing torsional angles and calculating resulting energies and
other stabilization parameters (so called ab initio approach). I could run
your peptide and see what comes out of it.
"Michael Steiper" <steiper at fas.harvard.edu> wrote in message
news:aitv1k$vol$2 at news.fas.harvard.edu...
> I have identified an aberrant alpha globin protein sequence and I would
> like to know if the peptide can fold into a functional protein. i don't
> want to know anything fancy, just some basics. are there any computing
> resources to help with this?
> please email steiper at fas.harvard.edu with any help.
> Laboratory of Molecular Anthropology, Department of Anthropology
> Harvard University
> lab#:617.495.8323 Peabody Museum
> office#:617.495.8323 11 Divinity Avenue
> www.fas.harvard.edu/~steiper/res.html Cambridge, MA 02138
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