Redox fusion partners

Emir Khatipov khatipovNO at
Thu Mar 7 11:24:47 EST 2002

Is that known why thioredoxin, GST stabilize otherwise insoluble proteins
when expressed in fusion? Could that be due to changes in conformation of
the fusion partner? Is stabilization related to redox properties of Trx and
GST, and how? Protection of disulfides that hold the structure together or
anything else? What's the general dogma?

Any leads and discussion will be much appreciated.


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