Peptide antibody design software: comments needed

Chang Zhu czhu at changbioscience.com
Sat May 11 02:19:48 EST 2002


I'm writing a program (Abie) to help selecting antigenic peptides for
making
antibodies. The software is now avaiablable online for testing at

http://antibody.changbioscience.com/

The software gives the user the option to select a peptide based on
hydophilicity, amino acid composition, and certain post-translational
modifications. But to the best of my knowledge, picking a peptide is
still an art. What will be the rules you use to pick a peptide with
the best chance to
succeed? If you have some good or bad experience, could you share them
so we can learn from your past success (or failure)? Thanks.

Chang Zhu




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