How long is a protein sequence?

Dr Engelbert Buxbaum engelbert_buxbaum at
Tue Dec 7 07:32:38 EST 2004

Stefek Borkowski wrote:

> Hi,
> Can someone explain how the length of protein sequence, i.e. the number of
> amino acid residues, should be properly counted. I try to assess the length
> of human heart fatty acid binding protein. It is physically built of 133
> amino acids, but for some reason the literature value is 132. It seems like
> the paper purposely omits the first methionine. Also the numbering of amino
> acids goes this way, as if the starting methionine is not present. Would you
> please comment on this. Thank you in advance. Regards,
> Stefek 

The leading Met is often clipped away during protein processing and not
present in the finished product.

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