protein interaction

Dr Engelbert Buxbaum engelbert_buxbaum at hotmail.com
Tue Oct 19 09:27:52 EST 2004


D.K. wrote:


> >Ionic and hydrogen bonds involve hydrophilic groups.
> 
> I am not an expert but perhaps for precisely this reason I 
> cannot offhand think of a case where specific high affinity 
> interaction occurs between highly acidic and highly basic faces of 
> two proteins. I am sure there are few cases like that but it's 
> probably more of an exception... 

This probably depends very much on the individual proteins. As example
for ionic interactions in proteins haemoglobin subunits (and Bohr
effect) would spring to mind...




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