[Protein-analysis] Re: Question about Hypothetical Thermal Injury of the Inner Ear

Kyle Legate legatek at hotmail.com
Thu Oct 27 15:07:09 EST 2005


Radium wrote:
> Radium wrote:
> 
>>DK wrote:
>>
>>
>>>If inner hair cells are all dead (and they *are* if their proteins are
>>>denatured), then the alterations in auditory perceptions to occur
>>>would be deafness.
>>
>>Any tinnitus? Any distortion in sound before complete deafness?
> 
> 
> What if only the IHCs of the ^apical^ membrane is affected?
> 
As opposed to inner hair cells of the basolateral membrane!?

I don't think I've ever laughed so hard at a bionet topic.

For your information "Radium" there is a Basilar membrane, a Tectorial 
membrane and a Vestibular membrane, there is no apical membrane.

http://www.medicine.mcgill.ca/physio/cullenlab/img209/vestcol_opt.jpg

To answer your madly impossible hypothetical question, deafness would 
occur. No distortion, nothing. No sound. Tinnitus is a neurological 
condition which may occur 20% of the time.


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