[Protein-analysis] Re: Question about enzymes

[Tom Anderson]

On Wed, 18 Oct 2006, Marvin wrote:

> yubbers9 from yahoo.com wrote:
>
>> I'm taking an introductory biology course, and I've been told that 
>> enzymes always have only one active site.
>
> An enzyme is often made up of two or more protein, held together by zinc 
> ions.

Er, or by other things, principally the hydrophobic effect. Any particular 
reason why you mention zinc?

> It is not uncommon to have two active sites for the same substrate 
> compound, and the two sites can interact, so that what is happening at 
> one site affects the other site.

Very true - this is known as 'cooperativity', and is a key concept in 
enzymology.

tom

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