[Protein-analysis] Help with calculations for specific activity

Fasulo, Lisa M via proteins%40net.bio.net (by lisa.m.fasulo from pfizer.com)
Tue Sep 30 15:55:26 EST 2008


I am trying to calculate the specific activity of my [3H]-ligand but
don't know how to do it.  The package insert for my radioligand states
that the Specific Activity is 200 mCi/g but I need to know what the
Specific Activity is in Ci/mmol.  How do I calculate this?  The
molecular weight of the radioligand is 463.6 g/mol.  Can anyone walk me
through the calculations to give the specific activity in Ci/mmol?  The
only other info I have is the concentration of the radioligand which is
1mCi/mL.

Lisa



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