EUROPEAN UNION - DG XII, Cooperation with Third Countries INCO-DC program
COSTB9 , European Cooperation in the Field of Scientific and Technical
Research
WORLD HEALTH ORGANISATION, Tropical Disease Research Programme
This is the second announcement (15/03/99) for an international symposium on
-------------------------------------------------------------
DRUGS AGAINST PARASITIC DISEASES
24th to 26th May 1999, Montpellier, France
-------------------------------------------------------------
Practical information :
http://162.38.196.39/drug-symposiumsymposia at univ-montp2.fr
Henri VIAL/ Christine BOUSQUET
UMR 5539 CNRS/Université Montpellier II, cc107
Place Eugène Bataillon
34095 Montpellier cédex 5, France
Tél. : (33) 4.67.14.42.87 Fax. : (33)
4.67.14.42.86
-------------------------------------------------------------
SCOPE OF THE MEETING
The meeting is being organized under the auspices of the European
Commission INCO-DC program, by the Tropical Diseases Research Branch of the
World Health rganisation and as the annual spring meeting of the European
Concerted Action on hemotherapy of Protozoal Infections (Cost action B9).
The symposium should offer pportunities for future collaborations and
discussions between these Institutions in such n important area. >This
meeting will provide experts in Parasitology, Biochemistry, cellular and
molcular Biology, Chemistry, Pharmacology, Toxicology, and research
managers with a forum in which to discuss advances and up-date their
knowledge concerning drug discovery in the area of parasitic diseases and
to provide facilities to accelerate drug evelopment in this crucial field,
and ways of improving control strategies. In addition, new research tools
are available such as genomics, genetic manipulaton. These represent
opportunities from basic research to the definition of operationa research.
Particularly, how to capitalise on information on the whole genome
approache of the parasite. What is the optimal utilisation of this
information ? Which of this biocheical pathways of these organisms can be
used for future drug development ?
We have invited prominent scientists and experts to present data on
up-to-date topics and would gladly welcome short communications or posters
you might have on the various topcs.
We hope hat this conference will strengthen the collaboration between
scientists, experts, an professionals both in the North and the South, thus
promoting excellence not only in resarch but also in practical
implementation.
------------------------------------------------------------
SCIENTIFC COMMITTEE
Croft, (London, UK)
Hagan (Glasgow, UK)
Horton (London, UK)
Kharazmi (Copenhagen, Denmark)
Lanzer (Heidelberg, D)
Perie (Toulouse, F)( Local Organizer)
Olliaro (Geneva, CH)
Opperdoes (Louvain, B)
Ridley (Geneva, CH)
Traore (INCO-DC, Brussels, and Mali)
Vial (Montpellier, F) (Local Organizer, Coordinator)
------------------------------------------------------------
RELIMINARY SCIENTIFIC PROGRAMME (15/03/99)
OPENING: GLOBAL PICTURE OF ANTIPARASITIC DRUGS AND NEED IN CNTROL STRATEGIES
Rob Ridley (WHO, Geneva, CH) : Parasitic disease: the need for new
approaches to tropical disease drug discovery and development for improved
control strategies.
Patrice Trouiller (Grenoble, F) : Drug development output for tropical
diseases : what ae the economic constraints ?
>>SESSION I: HOW TO DISCOVER NOVEL PHARMACOLOGICAL TARGETS: THE PRASITE
>>GENOMES, WHAT DO THEY PROMISE AND WHAT ARE THE LMITATIONS ?
>>- Alister Craig (Oxford, UK) : The international programme on P.
>>falciparum genome squencing; status and Post-Genomic Agenda.
> Sara Melville, (Cambridge, UK) : Organisation of the T. brucei genome
> David Parry Smith (Cambridge, UK) : Overview of Bioinformatics and
>Applications in Dug Discovery
>-Pierre Casellas (SANOFI , Montpellier, F) : DNA chips: applications in
>pharmacology
>-Chris Gray (Hofmann La Roche, Basel, CH) : Bacterial Targets and
>Antibiotics: Gnome-Based Drug Discovery (Proteomics and application to
>pathogens).
>-Daniel Lawson (Sanger Center, Cambridge, UK) : Mechanistics of
>Bioinformartics.
>-xxx : Use of genetic engineering for demonstrating potential for Efficacy.
>>SESSION II: COMPOUNDS ACQUISITION AND SEQUENTIAL STEPS FROM THE BNCH TO
>>THE THRESHOLD OF PRECLINICAL STUDIES OR RATIONAL FOR DRUG DVELOPMENT
>>- J. Martinez (CNRS, Montpellier, F): Combinatorial chemistry: a new
>>challenge in dug discovery
> xxx Natural sources. Search for potential antimalarial from natural
>sources (plants). Ehnopharmacology , bioassay guided fractionation and
>structure elucidation.
> A. Fairlamb, (Dundee, Scotland) : Trypanothione reductase and
>validation of this pathway as drug target by producing knock outs in
>leishmania.
> Micheal H. Gelb, (Seattle, USA) Protein Prenylation in Trypanosomatids:
>A New "Piggy-Back" Medicinal Chemistry Target for Drug Development
> Paul Michels (Louvain, Belgium) : On the mathematical modelling of
>metabolic pathways and its use in the identification of the most suitable
>drug targets. (he has acepted)
> P. Olliaro (WHO, Geneva) Rationale and Criteria for Drug combination.
>>SESSION III : METHODS FOR SCREENING OF POTENTIAL DRUGS. EVALUATION O
>>PHARMACOLOGICAL ACTIVITIES.
>>- Simon Croft, (London, UK) In vitro and in vivo models for antiprotozoal
>>activity - prpose and relevance
>- Alan Thomas (BPRC, Rijswijk, NL) : Models for the in vivo testing of
>potential compounds against malaria.
>- J Julio Martin (Glaxo Wellcome, Madrid, Spain) : Screening methodologies
>for chemotherapeutic targets. High throughput screening as an essential
>complement to the genomic approach. Advanced technology to assist high
>throughput screening
>- Pascal Ringwald, (IRD, Yaoundé, Cameroon) : In vitro and in vivo
>chemosensitivity testing of the malaria parasites (where, who, how ...).
>Worlwide dynamic of resistance.
>- Pradipsinh Rathod, (University, Washington, USA) : Induction of
>resistance: when to ask this question and how to get an answer ?
>>SESSION IV: PRE-DEVELOPMENT WORK: HOW TO GO THROUGH THE CLINICAL STAGES.
>>- Thomas Wellems (Bethesda, USA) : The molecular basis of chloroquine
>resistance
>- Hagai Ginsburg (Hebrew University of Jerusalem) : Targets for malaria
>drug development derived from basic research
>- Robert G. Ridley (WHO/TDR, Geneva, CH) : Developmental compounds in the
>pipeline for treatment and/or prophylaxis of malaria.
>- Deborah Kioy (WHO, Geneva, CH) : Essential toxicological and
>pharmacokinetic data needed before preclinical studies
>- John Horton (SKB, London, UK) Various steps from preclinical phase to
>the clinical trials and marketing.
>>SESSION V: ECONOMIC CONSIDERATIONS CONCERNING ANTIPARASITIC DRUGS
>- Pascal MILLET, (Bordeaux, F) : How to create a link between fundamental
>research and the pharmaceutical industry in Tropical Medicine?
>- M. Traore (Mali, and INCO-DC, EU, Brussels, B) or Y. Yuthavong (Bangkok,
>Thailand) : Role of endemic countries in research and development.
>- Win Gutteridge (WHO/TDR, World bank, Geneva, CH) : The New Medicines
>for Malaria Venture (MMV)
>- Palle Hoy Jakobsen (Denmark) : Patent policy and strategies for
>tropical diseases: who and in which countries
>- John Horton (SKB, London, UK) : Private sector: defect of the industrial
>partner or lack of good compound.
>>-------------------------------------------------------------
>LOCATION:
>>The Symposium will be held at " LE CORUM ", Conference and Culture Centre
>in the heart of Montpellier, easily accessible from the "Montpellier
>Méditerranée" Airport, and the TGV high speed train station.
>Montpellier is Situated in the South of France, only a few miles from the
>Mediterranean Sea, Montpellier is the capital of the Languedoc-Roussillon
>Region.
>The international Montpellier-Mediterranée Airport is served by several
>international companies, including Air-France, British-Airways and
>Air-Littoral. Around 20 connecting flights with Paris are organised by
>three different companies. A regular bus service links the airport to the
>city centre.
>The High Speed Train (TGV) links in four hours and several times per day
>Montpellier with Paris. The TGV Railway Station is only five minutes
>walking distance from the "Corum" Conference and Cultural Centre.
>>The A9 motorway passes by Montpellier. The easiest exit to reach the Corum
>Conference and Cultural Centre is "Montpellier-Est". Cars can be parked in
>the "Corum" Centre basement parking (Charge).
>-------------------------------------------------------------
>PRACTICAL INFORMATION
>>The full text of the second announcement, including the electronic form
>for congress registration and lodging reservation form is available on our
>Web site at the following address : http ://162.38.196.39/drug-symposium/.
>Participants are encouraged to use electronic registration and
>accommodation form for lodging.
>For Hotel reservations : May 1st 1999 (See below)
>We invite you to register your travel arrangement and reserve your hotel
>as soon a possible. Indeed, the internal and, may be, international
>flights, may be overcrowded on this week end, as will be the hotels.
>>-------------------------------------------------------------
>ORAL OR POSTER CONTRIBUTIONS: DEADLINES AND INSTRUCTIONS FOR THE
>PREPARATION OF ABSTRACTS
>>Participants wishing to present a contribution should submit an abstract
>following the format detailed below, not later than 26 March 1999 (oral
>contribution), or 15 April (poster contribution), to the address indicated
>above (secretariat of the conference).
>Full one-page abstracts will be reproduced directly from the authors'
>original documents. These should be typed using A4 formatted paper with
>the following format: Title (in bold), Author's names (NAME, I.N. in
>roman), Author's affiliation (in italic), body text (one column) They
>should have a length of approximately 400 words including title and
>eventual references. The name of the person presenting the paper should be
>underlined. Eventual references should be indicated within brackets in the
>text and listed at the bottom of the abstract. Abstracts should be
>submitted by e-mail (as attached file) to the following address:
>symposia at univ-montp2.fr, or failing that, on diskette (PC is
>preferred)(rtf file is the most appropriate), accompanied by two copies of
>the printed version, to the conference secretariat.
>Accepted papers for oral and poster contributions will be included in the
>conference programme and the book of abstracts only after receipt of the
>registration fees. However, the inclusion of presentation as an oral
>communication will be dependent on the final scientific programme, as
>numbers will be limited. You will be informed of our decision before
>April 26th. If not included as an oral communication, you will be invited
>to present your paper as a poster. The abstract book including all
>lectures and oral and poster contributions will be handed out to the
>registered participants upon arrival.
>>-------------------------------------------------------------
>REGISTRATION/ PAYMENTS
>>The registration fees covers the following items :
>1. Participation in the Scientific Programme
>2. Conference material
>3. Volume of abstracts
>4. 3 lunches + 1 cocktail
>5. Coffee breaks
>The banquet is not included in the registration fees.
>All bank charges must be paid by the participant and your signature is
>essential for your registration.
>>DEADLINES :
>Your registration will take effect from the moment when the payment
>arrives at our office. Accepted papers for oral and poster contributions
>will be included in the conference programme only after receipt of the
>registration fees. Registration will be confirmed if payment is received
>at the conference office by 30.04.1999. If your registration cannot arrive
>by 30.04.1999, you should register at the conference Office immediately
>after your arrival.
>>-------------------------------------------------------------
>REGISTRATION FORM (CUT HERE)
>>I hereby register for participation in the the Symposium DRUGS AGAINST
>PARASITIC DISEASES
>>TITLE (Dr, Mr, Ms etc.).... SURNAME....................FIRST
>NAME......................
>INSTITUTION/COMPAGNY...........................................................
>........
>ADDRESS........................................................................
>........
>...............................................................................
>........
>>TEL............................ FAX..........................
>E-MAIL..................................................................
>>I intend to present a paper/poster entitled :
>...............................................................................
>..........
>...............................................................................
>..........
>.........................................
>at session: ...............................................................
>>Registration...................Before 15/04/1999..............After 15/04/1999
>Regular participant ...........1.200 FF or 213 US$............1.500 FF or
>266 US$
>CNRS participant...............1.000 FF.......................1.200 FF
>*Participation at the banquet .........350 FF or 62$
>(optional)
>TOTAL
>AMOUNT...................................................................
>>HAS BEEN PAID THIS DAY BY /
>Bank transfer : Please indicate your name and the title of the symposium,
>domiciliation : tpmontpellier trésorerie générale - code banque : 10071 -
>code guichet : 34000 - n° de compte : 00003003417 - clé RIB : 66.
>or
>Purchase order or Bank cheque in Francs or Dollars, made out to "Agent
>Comptable du CNRS ".
>Please write on your registration form the total amount (conference fees,
>and eventually banquet).
>>Signature:
>>Please fill in and return the enclosed registration form as soon as
>possible. All registrations, cancellations and alterations should be sent
>to :
>>Conference Secretariat:
>Mme Christine BOUSQUET
>UMR 5539 CNRS/Université Montpellier II, cc107
>Place Eugène Bataillon
>34095 Montpellier cédex 5
>Tél. : (33) 4.67.14.42.87 Fax. : (33) 4.67.14.42.86
>E.Mail : symposia at univ-montp2.fr>http://162.38.196.39/drug-symposium/.>>-------------------------------------------------------------------------------
>----
>HOTEL ACCOMMODATION
>DIRECTLY BY « LE CORUM »
>>All participants have to fill in the attached form and send directly to «
>Le Corum » who will arrange reservations in hotels. We invite you to
>register your travel arrangement and reserve your hotel as soon a
>possible. Indeed, the internal and, may be, international flights, may be
>overcrowded on this week end, as will be the hotels.
>>-------------------------------------------------------------------------------
>----
>ACCOMODATION FORM (CUT HERE)
>DRUGS AGAINST PARASITIC DISEASES
>MAY 24/26, 99
>>FILL IN ONE REGISTRATION FORM PER PARTICIPANT IN CAPITAL LETTERS
>-SEND IT BACK WITH THE PAYMENT ENCLOSED BEFORE MAY 1st, TO :
>>STE LE CORUM - SERVICE CONGRES - BP 2200 - Esplanade Charles de Gaulle -
>34027 MONTPELLIER CEDEX1 - FRANCE
>Tel : 33 (0) 4 67 61 67 61/ Fax : 33 (0) 67 61 66 84
>e.mail : corum at gestion-montpellier.fr>>Mr Mrs Drr Pr
>>>FAMILY NAME FIRST NAME
>>>ADRESS
>>>>>ZIP CODE CITY
>>>>COUNTRY
>>>PHONE FAX
>>>PLEASE RESERVE A HOTEL : 4 H 3 H Chain 3 Tradition H
> 2 H
> or second choice
>>>.....room(s) for ......person(s) Single Double
> twin beds
>>>I will arrive at Montpellier on May ......... and will leave on
>May..........
>>ACCOMMODATION FEE
>CLASS PRICE MINI-PRICE MAXI DEPOSIT AMOUNT
>4 H 625 FF - 700 FF 565 FF x..........
>3 H Chain 480 FF - 600 FF 465 FF x..........
>3 H Tradition 380 FF - 500 FF 365 FF x...........
>2 H 300 FF - 400 FF 265 FF x...........
>Tourist tax not included
>>The table above indicates the approximate price for each room per night,
>with breakfast,V.A.T and service included (valid until December 31, 1999
>subject to change without notice
>For accommodation, the deposit amount includes 65 FF for processing.(i.e :
>Amount ex-VAT : 53,90 FF / VAT 20,60% 11,10 FF)
>Only applications received with payment enclosed will be considered.
>Accommodation forms received after May 1st, upon availability only.
>CANCELLATION : Deposits will be refunded only upon written cancellation
>addressed to LE CORUM (letter, fax or E.Mail) at least 15 working days
>before the beginning of the Congress. A fee of FF 65 (taxes included) will
>be deduced for processing
>>PAYMENTS BY CHECKS : Please make your check payable to CORUM / HEBERGEMENT
>>PAYMENTS BY SWIFT TRANSFER :.Code Swift : BWOR - FRPP.
>CORUM / HEBERGEMENT - N° 08 401 57 894 N - Banque WORMS, 8 Bd Ledru
>Rollin, 34000 MONTPELLIER. - FRANCE
>PLEASE INFORM YOUR BANK THAT THE TRANSFER FEES MUST BE PAID BY THE ISSUER.
>>PAYMENT: CHECK SWIFT TRANSFER
>>THE FORM SENT BY INTERNET DOES NOT REPRESENT A HOTEL RESERVATION.
>ONLY THE FORMS SENT BY MAIL WITH THE PAYMENT ENCLOSED WILL BE PROCESSED.
>DATE SIGNATURE :
>>>>>Symposia at univ-montp2.fr>http://162.38.196.39/drug-symposium>Henri VIAL/ Christine BOUSQUET
>UMR 5539 CNRS/Université Montpellier II, cc107
>Place Eugène Bataillon
>34095 Montpellier cédex 5, France
>Tél. : (33) 4.67.14.42.87 Fax. : (33) 4.67.14.42.86
>personal e-mail: vial at univ-montp2.fr>
