Adequate Uncertainty Factor for Exposure Limit

Stephen Soileau soileau at purple.tmn.com
Wed Oct 11 07:43:18 EST 1995


I would suggest that the 25 fold uncertainty factor is too small unless 
the mechanism of carcinogenicity is well understood.  I would consider a 
safety factor of 100 to be a BARE minimum if nothing is known about the 
mechanism of action.

Steve Soileau, Ph.D., D.A.B.T.




More information about the Toxicol mailing list