Lead Toxicity in Fish

Craig Thompson thompson at super.zippo.com
Mon Apr 29 11:18:06 EST 1996


In article <4m0v97$4pv at newsbf02.news.aol.com>, markblake7 at aol.com says...
>
>Does anyone know what the concentration of lead in fish is that will
>elicit a risk of 1 in 1,000,000 toxicity or carcinogencity, assuming the
>average human mass of 70 kg and average consumption of fish 20 g/day?

In article <4m0v97$4pv at newsbf02.news.aol.com>,
   markblake7 at aol.com (MarkBlake7) wrote:

>Does anyone know what the concentration of lead in fish is that will
>elicit a risk of 1 in 1,000,000 toxicity or carcinogencity, assuming 
the
>average human mass of 70 kg and average consumption of fish 20 g/day?

More complex than that.

Need a bioconcentration factor (established by the EPA and derived from 
section 304 of the CWA)

Need a diet fraction -- i.e., the percentage of tota fish in the 
individual's diet that comes from the contaminated source.

Lead toxicity is generally modeled on blood concentrations in humans.

You might find what you're looking for in EPA's "LEAD ).5, A PC 
Software Application of the Uptake/Biokinetic Model" January 1991

BTW 20 g/day is pretty low. Depends on where you're at of course (We 
eat a lot of fish and shellfish in Washington State)

Craig Thompson
WA State Dept of Ecology




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