DETERMINE CARDIAC OUTPUT IN ANIMALS
75144.2413 at CompuServe.COM
Tue Aug 20 14:25:02 EST 1996
During the last decade, the production of transgenic mice, with
different gene expression provided a valuable tool for the study
of genes involved in cardiovascular functions in recipient. In
small animal, the hemodynamic measurement is very limited because
of the animal size. The most important and basic cardiovascular
parameters, considered by physiologists and pharmacologists, are
cardiac output, blood pressure, heart rate and stroke volume.
Despite the plethora of instruments currently available for
studying the above mentioned parameters in laboratory animals, no
such instrument can measure all four parameters simultaneously.
We developed a device which measures not only all the above
mentioned parameters but also measures in wide range of animals
that is from mice to horses. This procedure is thermodilution and
is widely accepted by different scientists. If you like to
receive the description of instruments along with the procedure
in different animals, please e-mail your street address.
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