Cytochrome P450

Rohan H. Wickramasinghe rohan at ites.ac.lk
Wed Apr 16 12:51:45 EST 1997


Hello,

Some time ago we published some papers relating to cytochrome
P450 proteins and their activities. We would be very grateful for
any information as to whether any of the work noted below has been
followed up and for any relevant references (esp. in conference
proceedings, books etc.).

The publications concerned were:

1) R.H.Wickramasinghe, " Regulation of corticosteroid
   hydroxylations: the intramitochondrial dielectric constant and
   proteolipids of adrenodoxin and cytochrome P450 ", CYTOBIOS
   (Cambridge, England) 8(1973)81-94,

2) R.H.Wickramasinghe, " The regulation of corticosteroid
   hydroxylations. 1. An effect of inorganic ions in regulating iron-
   sulphur protein-dependent electron transport ", JOURNAL OF
   BIOENERGETICS  5(1973)151-161,

3) R.H.Wickramasinghe and C.A.Villee, " Early role during chemical
   evolution for cytochrome P450 in oxygen detoxification ", NATURE
   256(1975)509-511,

4) R.H.Wickramasinghe and C.A.Villee, " Possible similar role of
   cytochrome P450 in primordial evolution of species and in chemical
   carcinogenesis " , PERSPECTIVES IN BIOLOGY AND MEDICINE
   19(1976)473-475,

5) R.H.Wickramasinghe, " Dielectric constants and lithium ion
   treatment of psychiatric illness ", Abstracts, 35th Annual National
   Meeting of the American Federation for Clinical Research, 30 April
   - 1 May 1978 at San Francisco, California, CLINICAL RESEARCH
   26(1978)297A,

6) R.H.Wickramasinghe, G.Mueller and K.Norpoth," Spectral evidence of
   interaction of spice constituents with hepatic microsomal
   cytochrome P-450 ", CYTOBIOS (Cambridge, England) 29(1980)25-27,

7) R.H.Wickramasinghe, " The effects of glutathione on the
   11beta-hydroxylation of 11-deoxycorticosterone by bovine adrenal
   cortex mitochondria ", BULLETIN OF ENVIRONMENTAL CONTAMINATION
   AND TOXICOLOGY  12(1974)99-103,

8) R.H.Wickramasinghe and G.T.Bryan, " Effect of progesterone on
   human corticosteroid 21-hydroxylation ", EXPERIENTIA
   31(1975)1366-1367.

Thank you very much for taking the time to read this and in advance
for any help you can give.

Regards,

Rohan H. Wickramasinghe




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