Chuck Miller rellim at MAILHOST.TCS.TULANE.EDU
Fri Mar 7 13:02:41 EST 1997

Hi Andrei,

Cycloheximide inhibits the peptidyl transferase activity of the 60S
ribosomal subunit, thus blocking the elongation step of protein synthesis.
It is specific for eukaryotic ribosomes--does not affect prokaryotic,
mitochondrial and chloroplast ribosomes.

For a reference see L.Stryer's "Biochemistry" 2nd. ed.(1981) p.662, or
several other molecular, cellular or biochemical texts.

Best of results,


Dr. Charles A. Miller, rellim at
Founder, Bionet.toxicology news group:
Dept. Environmental Health Sciences, SL29
Room 374, Center for Bioenvironmental Research
Tulane Univ. School of Public Health and Tropical Medicine
1430 Tulane Ave.
New Orleans, LA 70112

More information about the Toxicol mailing list