Liquid-liquid Extraction

Shayne Woodward Shayne_Woodward at discovery.umeres.maine.edu
Tue Jul 7 09:00:34 EST 1998


I need to measure levels of two inactive metabolites of
chloroacetaldehyde, 2- and 3- dechloroethylifosfamide, respectively. 
The apparent method for measurement is to use a technique called
liquid-liquid extraction (LLE) using ethyle acetate, then resolving on
a Chirasil-L-val GC column and then detected via a
nitrogen-phosphorous-selective flame ionization detector.  Does anyone
have any knowledge about this or know of a lab or company that could
run some plasma samples?  Any help is greatly appreciated.  Thanks in
advance.

Shayne Woodward
Surgical Research
Dartmouth College
Hanover, NH



More information about the Toxicol mailing list