Fw: Peer Review of Skin Cancer Risk From Coal Tar Shampoos

Chuck Miller rellim at mailhost.tcs.tulane.edu
Tue May 16 20:18:44 EST 2000


----- Original Message -----
From: Jacqueline Patterson <patterson at TERA.ORG>
Subject: Peer Review of Skin Cancer Risk From Coal Tar Shampoos


Independent Peer Review of Assessment of Skin Cancer Risk from Use of Coal
Tar-Containing Shampoos

An expert peer panel will be convened on June 5 and 6, 2000 to review a
document entitled "Estimation of Lifetime Skin Cancer Risk from the Use of
Coal Tar-Containing Shampoos." This document was prepared by the K.S. Crump
Group of ICF Consulting for Whitehall-Robins Healthcare, a subsidiary of
American Home Products. The review will be held at the University of
Cincinnati and will be open to the public. This independent peer review
meeting is held under the International Toxicity Estimates for Risk (ITER)
program of Toxicology Excellence for Risk Assessment (TERA).


The risk assessment document reviews the human and animal data on exposure
to coal tar and species differences that would impact species extrapolation
were considered. Using the epidemiology data on patients treated with coal
tar ointments, the 95% lower bound on the lifetime dose associated with the
target risk level of one in 100,000 was estimated. Monte Carlo analyses were
used to estimate the amount of coal tar ointment used, as well as estimate
the lifetime average daily intake for users of coal tar shampoos.

The peer review panel is made up of scientists from industry, government,
consulting, and academia, creating a balanced panel, while carefully
managing potential conflict of interest issues. The meeting will be open to
the public, but seating is limited. Observers must pre-register and there is
a registration fee to cover the cost of materials and breaks.

This independent peer review is organized by TERA; a non-profit corporation
dedicated to the best use of toxicity data for risk assessment. More
information about the peer review program, including a list of approved
reviewers and summaries of discussions from previous meetings can be found
at http://www.tera.org/peer . For more information or to register as an
observer, contact Jacqueline Patterson at (513) 521-7426 or email
patterson at tera.org.



Jacqueline Patterson
Toxicology Excellence for Risk Assessment
1757 Chase Ave.
Cincinnati, OH 45223
513-521-7426
fax 513-521-7428
www.tera.org



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