FW: DNA Repair Interest Group - UPDATE - May 14, 2003

Chuck Miller rellim at tulane.edu
Wed May 14 10:58:30 EST 2003


------ Forwarded Message
From: "Kenneth H. Kraemer" <khk at nih.gov>
Reply-To: Ken Kraemer <kraemerk at nih.gov>
Date: Wed, 14 May 2003 11:46:14 -0400
To: DNAREPAIR-L at LIST.NIH.GOV
Subject: DNA Repair Interest Group - UPDATE - May 14, 2003

DNA Repair Interest Group - UPDATE - May 14, 2003

1.      VIDEOCONFERENCE - May 20, 2003 - Tues 12:30 PM- Dr. Errol
Friedberg, Univ of Texas Southwestern, Dallas, Tx - Honest Jim Revealed-
The Writings of James D. Watson
2.      SPECIAL NIH DNA REPAIR LECTURES -  May 15, 2003 - Thu 11:00 AM  -
Dr. Kenneth Kraemer, NCI -  Genotype-phenotype Correlations in Human DNA
Repair Diseases and their Relationship to Cancer in the General
Population;
        May 16, 2003 - Fri 12:30PM - Dr. Vilhelm Bohr, NIA - Human
Premature Aging Proteins: Werner and Cockayne, Links Between DNA Repair
and Aging
3. CONFERENCES - Midwest DNA Repair Symposium;  American Society for
Photobiology; International Congress of Photochemistry; Gordon Conference
on Genetic Toxicology;  DNA Repair and Mutagenesis: from Molecular
Structure to Biological Consequences;  International Congress of
Photobiology
4. POST DOC AND EMPLOYMENT OPPORTUNITIES: Baltimore, MD; Research Triangle
Park, NC; New York, NY; Boston, MA; Portland, OR; Ontario, Canada; Boston,
MA; Saskatchewan, Canada; Washington, D.C.
5. COMMERCIAL REAGENT SOURCES
6. Electronic Contacts


1.0     DNA REPAIR VIDEOCONFERENCE:

May 20, 2003 - Tues 12:30 PM- Dr. Errol Friedberg, Univ of Texas
Southwestern, Dallas, Tx - Honest Jim Revealed- The Writings of James D.
Watson - Origin: Smithville

VIDEOCONFERENCE LOCATIONS: ; Building 45 (NATCHER) Room H, Bethesda, MD;
Room 1E03 GRC Baltimore, MD Lawrence Livermore Labs, Livermore, CA; Univ
of Michigan, Ann Arbor; University of Pittsburgh; MD Anderson, Smithville,
TX (origin); Building 101 Room B200, NIEHS, Research Triangle Park, NC;
State University of New York, Stony Brook, NY; Univ of Kentucky,
Lexington, KY; Building 549, Conference Room A,  FCRDC, Frederick, MD;
Brookhaven National Labs, Upton, NY; Univ of Texas, Galveston and live on
the internet at http://videocast.nih.gov


1.1     DNA REPAIR VIDEOCONFERENCE - FUTURE DATES AND VIDEO ARCHIVE
[Note: A larger and more up to date list of future and past
videoconferences can be found on the DNA Repair Interest Group web site:
http://www.nih.gov:80/sigs/dna-rep/ ]

1.1.1 FUTURE VIDEOCONFERENCES:
Note: The talk by Dr. Susan Wallace scheduled for Feb 18, 2003 was snowed
out and will be rescheduled for next season.


June 17, 2003 - Tues 12:30PM - 3 Short Talks - Dr. John Bradsher, NCI,
NIH, Roles of the CS proteins in Nucleotide Excision Repair and
Transcription; Dr. Tom Rosenquist, SUNY, NEIL proteins and base excision
repair in mice; Dr. Karen Vasquez, Smithville, TX - Processing of
site-specific DNA lesions by DNA repair and recombination pathways


1.1.2 VIDEOARCHIVES: INTERNET ACCESS (WORLDWIDE):
To date 54 of these videoconferences have been archived and are available
for viewing at your leisure on the internet. You will need a web browser
(with a high speed link) and free Real Video software.  Setup details and
access are available at the NIH videocast website:
http://videocast.nih.gov. Go to Past events; DNA Repair Interest Group
Sessions.

Note: Technical improvements are made regularly on this site to increase
transmission speeds and ease of access. If you were not successful in
viewing these videos in the past it is worth trying again!

Apr 15, 2003 - Dr. Qingyi Wei, M.D. Anderson, Houston, Tx - DNA Repair
Function, Polymorphisms and Cancer Risk in the General Population

Mar 11, 2003 - Dr. Sankar Mitra, Univ of Texas, Galveston - Oxidative
Damage Repair and Its Co-ordination in the Mammalian Genome.[Note: The
posting of this talk will be delayed at the request of the speaker.]

March 05, 2003  - Dr. Stephen J. Elledge - Baylor College of Medicine
Houston, TX  - Sensing and Responding to DNA Damage  [Note: this talk was
part of the NIH Wed afternoon lecture series and was sponsored by: the
Mouse Club and Washington Area Yeast Club Interest Group and is now posted
on the DNA Repair Interest Group part of the videocast.nih.gov website.]

Jan 21, 2003 - Tues 12:30PM - Dr. Jack Taylor, NIEHS - Epidemiologic
studies of DNA repair gene polymorphisms and cancer risk

Dec 17, 2002 - Dr. John Tainer, UC Berkeley - Conformational Controls and
DNA Repair Coordination - [Note: The posting of this talk will be delayed
at the request of the speaker.]

Nov 12, 2002 - Dr. Rob Sobol, Univ of Pittsburgh - DNA Base Damage and
Repair Intermediates: Out of the Pan and into the Fire [Note: The posting
of this talk will be delayed at the request of the speaker.]

Oct 15, 2002 - Dr. Al Fornace, NCI - Convergence of the p53 and MAP kinase
stress signaling pathways after UV radiation

Sept 17, 2002 - Dr. Dale Ramsden, UNC - DNA Double strand break repair

June 18, 2002 - Dr. David Chen - Lawrence Berkeley National Lab - Role of
DNA-PK in Cellular Responses to DNA damage

May 21, 2002 -  Dr. Mark J. Schofield - NIH, Bethesda - DNA mismatch
repair; Dr. Sunitha Yanamadala - Univ of Michigan - Role of Mismatch
Repair Proteins in Signaling p53 and Apoptosis; Dr. Federica Marini - Univ
of Pittsburgh - A human DNA helicase homologous to the DNA crosslink
sensitivity protein mus308

Apr 16, 2002 -  Dr. Philip Hanawalt - Half a century of DNA repair: An
historical perspective

Mar 19, 2002 - Dr. Alan Tomkinson - Univ of Texas, San Antonio -
Mechanisms of DNA End Joining

Feb 19, 2002 - Dr. Yves Pommier - NCI - Nucleotide excision
repair-dependent cytotoxicity of a novel anticancer agent, ecteinascidin
743

Jan 15, 2002 - Dr. Tom Kunkel- NIEHS - Recent studies of DNA Mismatch
Repair

Through the miracle of videotape we now have been able to post most of the
DNA Repair Interest Group videoconferences from 1998,1999, 2000 and 2001
on the web site.  These include talks by Drs. Anderson, Beernik,
Bogenhagen, Bohr, Brash, Brooks, Brosh, Chu, Cleaver, Copeland,
Drotschmann, Emmert, Essigman, Fornace, George, Glazer, Grossman,
Hanawalt, Jin, Kashlev, Kraemer, Kunkel, Leadon, Liu, Ljungman, Matson,
Matsumoto,  McKay,  Setlow, Sharan, Sobol, States, Stefanini, Sung,
Sutherland, Thompson, Wang, Wood, Woodgate and Yarosh.

2. SPECIAL NIH DNA REPAIR LECTURES [Note: These talks will not be
videotaped]

2.1 May 15, 2003 - Thu 11:00 AM  - Dr. Kenneth Kraemer, NCI -
Genotype-phenotype Correlations in Human DNA Repair Diseases and their
Relationship to Cancer in the General Population; Location: Building 37,
Room 1A19

2.2. May 16, 2003 - Fri 12:30PM - Dr. Vilhelm Bohr, NIA - Human Premature
Aging Proteins: Werner and Cockayne, Links Between DNA Repair and Aging;
Location: Building 37 Room 4041


3.    CONFERENCES - Midwest DNA Repair Symposium;  American Society for
Photobiology; International Congress of Photochemistry; Gordon Conference
on Genetic Toxicology;  DNA Repair and Mutagenesis: from Molecular
Structure to Biological Consequences; International Congress of
Photobiology

[Note: A larger and more up-to-date list of conferences can be found on
the DNA Repair Interest Group web site:
http://www.nih.gov:80/sigs/dna-rep/ ]

3.1 5th ANNUAL MIDWEST DNA REPAIR SYMPOSIUM - MAY 23-24, 2003

Sponsor: Mayo Comprehensive Cancer Center, Cancer Cell Biology Program,
Department of Biochemistry and Molecular Biology
Location: Mayo Clinic Rochester,MN; Leighton Auditorium

Keynote Speakers:
Philip C. Hanawalt, Ph.D., Stanford University
Thomas A. Kunkel, Ph.D. NIEHS
John A. Tainer, Ph.D. The Scripps Research Institute

Symposium Host: Cynthia T. McMurray, Ph.D.

Speakers selected from abstracts, $250 prize for best poster

Information: http://www.mayo.edu/research/dnarepair



3.2 AMERICAN SOCIETY FOR PHOTOBIOLOGY - 31ST ANNUAL MEETING - BALTIMORE,MD
JULY 5-9, 2003

CALL FOR ABSTRACTS The Program Committee requests all invited speakers to
submit abstracts of their presentations, and solicits contributed
abstracts for oral or poster presentation from all interested scientists.
Rules for abstract submission and procedures for submitting on-line are
given at
http://abstracts.allenpress.com/cgi-bin/phot/index.pl
SUBMISSION DEADLINE: April15, 2003


3.3 INTERNATIONAL CONFERENCE ON PHOTOCHEMISTRY, NARA, JAPAN - JULY 26-31,
2003

Dear Colleague;

On behalf of the International Committee and the Local Organizing
Committee it is my great pleasure to invite you the XXIst International
Conference on Photochemistry to be held in Nara, Japan from July 26 to 31,
2003.

The 1st Circular can be found at the www page at
http://dolphin.ap.eng.osaka-u.ac.jp/icp21.html.
If you wish to receive the second circular in December, 2002, please
complete the REPLY FORM at the end of this mail and return it at your
earliest convenience by e-mail (or FAX). The REPLY FORM is also available
in the 1st Circular.

If you have any questions, please feel free to e-mail to the Secretary
General of the
Conference.

Sincerely Yours,
Professor H. Masuhara, Chairperson
XXIst International Conference on Photochemistry
Department of Applied Physics
Osaka University, Suita,
Osaka 565-0871, Japan

Professor K. Obi, Chairperson
XXIst International Conference on Photochemistry
Department of Chemistry
Japan Woman's University, Bunkyou-ku,
Tokyo 112-8681, Japan
All correspondence concerning the Conference should be addressed to:
Professor N. Nakashima, Secretary General
XXIst International Conference on Photochemistry
Department of Chemistry, Osaka City University,
Sugimoto, Sumiyoshi, Osaka 558-8585, Japan
E-mail : icp21 at sci.osaka-cu.ac.jp
phone &Fax: +81-6-6605-2552


3.4 GORDON RESEARCH CONFERENCE ON GENETIC TOXICOLOGY -QUEEN'S COLLEGE,
OXFORD, UK - AUGUST 10-15, 2003

Chair: Penny Jeggo, Genome Damage and Stability Centre, Sussex University
Vice Chair: Ben Van Houten, National Institute of Environmental Health
Sciences, NIH.

An exciting programme has been arranged for the Genetic Toxicology GRC,
which aims to bring together basic scientists working in the DNA damage
response field and more applied scientists in the field of genetic
toxicology. The detailed programme can be seen on the GRC web site and
registration made from the web site:
http://www.grc.org/programs/2003/gentox.htm.


3.5  DNA REPAIR AND MUTAGENESIS: FROM MOLECULAR STRUCTURE TO BIOLOGICAL
CONSEQUENCES - BERMUDA, DECEMBER 7-13, 2003.

Dear Colleagues,We are writing to let you know that we will be organizing
an ASM Conference entitled "DNA Repair and Mutagenesis: From Molecular
Structure to Biological Consequences" sponsored by the American Society
for Microbiology to be held at the Fairmont Southampton Princess, Bermuda,
December 7-13, 2003. The conference will bring together the various
subdisciplines that collectively comprise the field of DNA Repair and
Mutagenesis. Meetings of this type have been held at approximately four
year intervals since 1974, the preceding one in this informal series
having been at Hilton Head, South Carolina in 1999, and have played a
critical role in the development of this exciting area of research.

Speakers will include: Genevive Almouzni, Lorena Beese, Serge Boiteux,
Jaap Brouwer, Keith Caldecott, Judith Campisi, Gilbert Chu, Priscilla
Cooper, Titia de Lange, John Diffley, Sylvie Doubli, Jean-Marc Egly,
Stephen Elledge, Tom Ellenberger, Rick Fishel, Marco Foiani, Errol
Friedberg, Robert Fuchs, James Haber, Fumio Hanaoka, Phil Hanawalt, Jan
Hoeijmakers, Peggy Hsieh, Ian Hickson, Stephen Jackson, Maria Jasin, Penny
Jeggo, Joe Jiricny, Roland Kanaar, Richard Kolodner, Stephen
Kowalczykowski, Thomas Kunkel, Tony Leadon, Alan Lehmann, Tomas Lindahl,
Bndicte Michel, Sankar Mitra, Paul Modrich, Leon Mullenders, Tanya Paull,
John Petrini, Louise Prakash, Miroslav Radman, Rodney Rothstein, Leona
Samson, Alain Sarasin, Erling Seeberg, Jesper Svejstrup, John Tainer,
Shunichi Takeda, Kiyoji Tanaka, Graham Walker, Susan Wallace, Stephen
West, Sam Wilson, Richard Wood, Roger Woodgate, and Wei Yang.

Some additional speakers on timely topics will be invited closer to the
date of the meeting, and furthermore, speakers will be chosen from among
the submitted abstracts for shorter presentations.

Careful thought has been given to the choice of the site and the design of
the program so that participants will be able to enjoy the type of
opportunities for informal discussions and interactions that are normally
found only at smaller meetings. A special feature of the meeting will be
travel grants to help support the participation of graduate students and
postdoctoral fellows. Additional information concerning the meeting and
the program is available at: http://www.asmusa.org/mtgsrc/dnarepair2.htm

We hope you will mark these dates on your calendars. We look forward to
seeing you in Bermuda in December 2003!

Best Wishes
Graham Walker, Susan Wallace, and Priscilla Cooper

3.6 INTERNATIONAL CONGRESS ON PHOTOBIOLOGY - JEJU ISLAND, KOREA - JUNE
10-15, 2004.

The 14th International Congress on Photobiology sponsored by the
International Union of Photobiology and hosted by the Korean Society of
Photoscience, Photobiology Association of Japan, and Asia and Oceania
Society for Photobiology will be held June 10-15, 2004, on the island of
Jeju, Korea. Both Korean Society of Photoscience, Korean Photodynamic
Association, and Asia and Oceania Society for Photobiology will also hold
their annual meetings in conjunction with the Congress at the same time.
More details can be found at:
http://photos.or.kr/ICP2004 (ICP is case-sensitive)

I would like to invite you to register to participate in the Congress by
visiting the website and filling out the registration form therein. To
make the Congress successful, your suggestions and contributions are
essential and will be greatly appreciated by the Organizing Committee. In
order to make the Congress scientifically attractive, we plan to organize
nearly 50 symposia and 10 special lectures. In addition, we are planning
to present a national photobiology-society sponsored Plenary Lecture each
day of the
Congress.

The Congress venue is the Island of Jeju. It is one of the most beautiful
islands in the world. It offers many sightseeing and leisure attractions.
Bring your family and friends. You will enjoy it.

See you all here in Jeju, Korea, in Year 2004!

Best wishes,
Pill-Soon Song
Congress President-ICP2004

4.      POST DOC AND EMPLOYMENT OPPORTUNITIES: Baltimore, MD; Research
Triangle Park, NC; New York, NY; Boston, MA; Portland, OR; Ontario,
Canada; Boston, MA; Saskatchewan, Canada; Washington, D.C.  [Note: Check
the list for more Job Opportunities on the DNA Repair Interest Group web
site: http://www.nih.gov:80/sigs/dna-rep/ ]

4.1 NIH POST DOCTORAL FELLOW - DNA HELICASES- NIA, BALTIMORE, MD
With nation-wide responsibility for improving the health and well being of
all Americans, the Department of Health and Human Services oversees the
biomedical research programs of the National Institutes of Health and
those of NIH's research Institutes.

The National Institute on Aging, a major research component of the
National Institutes of Health (NIH) and the Department of Health and Human
Services, is recruiting for a NIH postdoctoral fellow to conduct research
program in The Unit on DNA Helicases, Laboratory of Molecular Gerontology.
An individual is sought who will complement our current research
activities that investigate structure-function aspects of DNA helicases
defective in premature aging and cancer disorders.  The objective of this
research is to understand the molecular-cellular roles of human DNA
helicases in pathways important for the maintenance of genome stability.

The successful individual will possess an M.D. or Ph.D., have research
experience in biochemistry, and training in molecular and/or
mammalian/yeast cell culture techniques.

For additional information on this position, and for instructions on
submitting your application, please see contact:  Robert M. Brosh, Jr.,
Ph.D., Investigator NIA-NIH, Laboratory of Molecular Gerontology, 5600
Nathan Shock Drive, Baltimore, MD 21224 USA.  Phone: 410-558-8578, E-mail:
BroshR at grc.nia.nih.gov

4.2 NIH POSTDOCTORAL POSITION - GENOME STABILITY - RESEARCH TRIANGLE PARK,
NC

NIH POSTDOCTORAL POSITION to investigate highly relevant genome stability
issues using yeast and/or human cell systems.  Research projects are
available in several related directions that include i) DNA double-strand
breaks (origin, repair, recombination, replication, cell signaling, and
real time analysis); ii) replication and mutation avoidance; iii)
influence of mitochondria on genome stability; and iv) human p53 function,
role in genome stability and model for evolution of regulatory networks
(see http://dir.niehs.nih.gov/dirlmg/home.htm).  A variety of genetic,
molecular, and functional genomics approaches are used that have been
developed in this Section. Along with exceptional facilities and
resources, the Section provides a highly interactive and unique scientific
environment with several areas of expertise, so as to create an
exceptional training opportunity.

The Section is part of the Laboratory of Molecular Genetics (LMG) with
many PI's renowned for their contributions to the area of genome stability
and is located at the National Institute for Environmental Health Sciences
(NIEHS) of the NIH.  NIEHS is in a highly attractive area of North
Carolina that is central to prominent research institutions.  A unique
feature of the postdoctoral program is the opportunity to apply for
special grants for subsequent tenure-track academic appointments. Salary
and benefits are competitive.

Application.  Send CV & names of references to Dr. Michael Resnick, Head,
Chromosome Stability Section, NIEHS, P.O. Pox 12233, Research Triangle
Park, NC  27709; resnick at niehs.nih.gov

        4.3 POST DOCTORAL POSITION - COLUMBIA UNIVERSITY, NEW YORK
A postdoctoral position is available immediately at the Department of
Radiation Oncology, Center for Radiological Research, Columbia University
to pursue studies of signal transduction pathway(s) involved in radiation
induced DNA damage and bystander response in mammalian cells. Candidate
with a recent a Ph.D. degree in Biochemistry, Molecular biology or Cell
biology is required. Experience in cell culture, protein biochemistry and
signal transduction research experience is preferred.
Interested candidates can submit their resume, areas of research interests
and three letters of recommendations to either
Prof. Charles R. Geard or Dr. A.S. Balajee
Department of Radiation Oncology
Center for Radiological Research
College of Physicians and Surgeons
Columbia University, VC-11, Room 243
168th Street, 630 West
New York, NY 10032.
Informal enquiries can be made to Dr. A.S. Balajee (ab836 at columbia.edu).

        4.4 POSTDOCTORAL POSITION - ALKYLATION DAMAGE - BOSTON, MA
Postdoctoral position - Biological Engineering Division Massachusetts
Institute of Technology, Boston, MA.  A postdoctoral position is available
in the lab of Leona D. Samson to study the biological effects of
alkylation damage.  Research areas include: (1) exploring the molecular
basis of cellular signaling in response to DNA alkylation damage; (2)
alkylation damage-induced global transcriptional responses; (3) functional
genomic approaches (genomic phenotyping) to identifying novel recovery
pathways; (4) transgenic and knockout mice to study the influence of
alkylation damage on apoptosis, mutation, genome stability and
tumorigenesis; (5) gene therapy approaches to suppressing bone marrow
toxicity.  Experience in biochemistry, molecular biology, cell biology,
DNA repair, or knockout/transgenic mouse technology is desired.
Selected Publications:
Hickman, M. and Samson, L.D. (1999) Role of DNA mismatch repair and p53 in
signaling induction of apoptosis by alkylating agents. Proc. Natl. Acad.
Sci., 96: 10764-10769.
Roth, R.B., and Samson, L.D. (2000) Gene transfer to suppress bone marrow
alkylation toxicity.  Mutation Research, 462:107-120.
Lau, A.Y., Wyatt, M.D., Glassner, G., Samson, L.D., and Ellenberger, T.E.
(2000) Molecular basis for discriminating between normal and damaged bases
by the human alkyladenine glycosylase, AAG. Proc. Natl. Acad. Sci,
97(25):13573-13578.
Jelinsky, S., Estep, P., Church, G., and Samson, L. D. (2000) Regulatory
networks revealed by transcriptional profiling of damaged Saccharomyces
cerevisiae cells:  Rpn4 links base excision repair with proteasomes,
Molecular and Cellular Biology, 20 (21):8157-8167.
 Roth, R. and Samson, L.D. (2002) 3-methyladenine DNA
glycosylase-deficient Aag null mice display unexpected bone marrow
alkylation resistance, Cancer Research 62, 656-660.
Begley, T.J., Rosenbach, A.S., Ideker, T. and Samson, L.D. (2002) Recovery
Pathways in S. cerevisiae Revealed by Genomic Phenotyping and Interactome
Mapping, Molecular Cancer Research, in press
Begley T.J. and Samson, L.D. (2003) AlkB mystery solved:  Oxidative
demethylation of N1-methyladenine and N3-methylcytosine adducts by a
direct reversal mechanism, Trends in the Biochemical Sciences, in press

Please send CV and 3 letters of Reference to:
Leona D. Samson
Ellison American Cancer Society Research Professor
Biological Engineering Division, and
Director of the Center for Environmental Health Sciences
Massachusetts Institute of Technology
77 Massachusetts Avenue, 56-235
Cambridge, MA 02139
or via email: lsamson at mit.edu

        4.5 POSTDOCTORAL POSITION-NERVOUS SYSTEM DNA REPAIR, PORTLAND, OR
A postdoctoral position is available immediately to study the role of DNA
damage and DNA repair in the nervous system. Particular emphasis is on
understanding the role of BER and NER in maintaining the integrity of
neurons and other cell types of the central nervous system. Currently
funded projects involve the use of whole animal and cell culture models
from transgenic/knockout DNA repair mutant mice to explore the
relationship between neuronal cell death and DNA damage during development
and in age-related neurodegenerative disease (e.g., Parkinson's,
Alzheimer's, and Lou Gehrig's disease). PhD candidates (less than 5 yrs
experience) with a strong background in molecular or cell biology and DNA
repair and experience in mammalian cell culture, protein biochemistry,
gene expression, protein-protein interaction, DNA microarrays are
encouraged to apply.

For more information, send an email to the address below. To apply, please
send your C.V., a description of your research experience, and the names,
addresses, telephone numbers and email addresses of three references to:


Glen Kisby, PhD
Associate ProfessorCtr for Res on Occup
& Environ Toxicol (CROET)
Oregon Health & Science University (OHSU)
3181 SW Sam Jackson Park Rd
Portland, OR 97201-3098
E-mail: kisby at ohsu.edu

Portland is an affordable centrally located city in the beautiful state of
Oregon. The University is only 1 h away from year round skiing at Mt Hood,
the Pacific Ocean, and the scenic deserts of eastern Oregon. The campus
contains a large group of distinguished faculty with special emphasis on
the nervous system. CROET is a unique research institute with faculty that
conduct applied research in the workplace (i.e., epidemiology) and basic
research at the cellular and molecular level.


        4.6 POSTDOCTORAL POSITION IN MAMMALIAN DNA REPAIR DEPARTMENT OF
BIOLOGY, McMASTER UNIVERSITY, ONTARIO, CANADA

A postdoctoral position is available immediately to study the DNA repair
pathways in mammalian cells. Our laboratory is particularly interested in
the mechanisms of inducible DNA repair pathways following exposure to UVA,
UVB and UVC and how deficiencies in DNA repair play a role in human
disease. Research areas include the role of several human ERCC genes in
inducible DNA repair as well as several aspects of the DNA repair
deficiency in cells from patients with xeroderma pigmentosum, Cockayne
syndrome, Li-Fraumeni syndrome and ataxia telangiectasia. Our laboratory
has developed a number of techniques to study DNA repair using
adenoviruses as probes and expression vectors and the application of these
techniques to other areas of mammalian DNA repair are also possible
research areas in my laboratory.

The position is initially for one year (minimum starting salary of
$30,000) with the possibility of extension for two further years.
Candidates with a recent Ph.D., a background in cell biology, molecular
biology and genetics, some experience in mammalian cell culture and a good
knowledge of both written and spoken English are encouraged to apply.
Please send a CV and the names and addresses (including email address and
telephone number) of three references to:

Andrew J. Rainbow, Ph.D.
Department of Biology
McMaster University
Hamilton, Ontario L8S 4K1
Canada.

Telephone: (905)-525-9140, ext. 23544
Fax: (905)-522-6066
Email: rainbow at mcmaster.ca
Website:
http://www.science.mcmaster.ca/biology/faculty/rainbow/rainbow.htm

        4.7 POSTDOCTORAL/RESEARCH ASSOCIATE POSITIONS - BOSTON
Two openings available immediately to study the role of AP endonuclease in
the cell physiology and biochemistry of DNA base excision repair.  We are
a dynamic group in a young department with lots of opportunity.  The
successful candidate will be smart, enterprising and hard working.  We
need you!
Contact:  Phyllis Strauss, Northeastern University, Boston MA 02115,
e-mail: p.strauss at neu.edu.

        4.8 POSTDOCTORAL POSITIONS - UNIVERSITY OF SASKATCHEWAN, CANADA

Two postdoctoral positions are available immediately. One is to study DNA
postreplication repair and mutagenesis in mammalian cells and in a
transgenic mouse model. The second position is to study molecular
mechanisms of gene regulation in response to DNA damage, using budding
yeast as a model eukaryote.

Candidates with recent Ph.D. and background in biochemistry, cell biology,
molecular biology and genetics are encouraged to apply. Annual salary
begins with $32,000 - $35,000, based on experience. Please send CV and
names of three references with contact information to:

Wei Xiao, Ph.D.,
Professor, Department of Microbiology and Immunology
University of Saskatchewan
107 Wiggins Road
Saskatoon, SK, S7N 5E5 Canada
Tel: 306-966-4308
Fax: 306-966-4311
E-mail: wei.xiao at usask.ca
Web site:http://www.usask.ca/medicine/microbio/xiaow/

        4.9 POSTDOCTORAL RESEARCH ASSOCIATE - WASHINGTON, D.C.
        An NIH funded post-doctoral position is available to investigate
the genetics of melanoma using a new mouse model of UV-induced melanoma
(Nature, 413:271-2, 2001) in particular to investigate the effect of
genetic deficiencies in nucleoside excision repair on melanoma induction.
Our laboratory has had a long term interest in the effects of UV radiation
in skin cancer. We have developed an exciting new model for melanoma which
most closely recapitulates human disease and represents a strong vehicle
for melanoma investigations. The George Washington University Medical
Center is currently expanding its interest in cancer research and through
the George Washington Institute of Biomedical Sciences is affiliated with
Children's National Medical Center, Red Cross Holland Laboratories and The
Institute for Genome Research.  Knowledge of DNA repair a strong
advantage. Excellent command of English is essential.
Please send applications to:
Dr F. Noonan, Professor, Department of Environmental and Occupational
Health, George Washington University Medical Center, Ross Hall, Rm 113,
2300 Eye St., NW, Washington DC, 20037.
Tel: 202 994 3970
email: drmfpn at gwumc.edu or fpn at gwu.edu
The George Washington University Medical Center is an equal opportunity
employer. GWUMC is conveniently located in downtown DC next to the Foggy
Bottom Metro.


        5. COMMERCIAL REAGENT SOURCES
[Note: There are more commercial reagent sources listed on the DNA Repair
interest group website: http://www.nih.gov:80/sigs/dna-rep/    These
sources are listed as a convenience to our readers and do not constitute
an endorsement of any of these companies or their products.]


5.1 Bethyl Laboratories, Inc.
Antibodies for DNA Damage/Repair and related research (www.bethyl.com)
New antibodies include SDS3, DMAP1, KIF14, DIS, MCM2, MCM3, MCM4, MCM6,
MCM7, MCM10, Claspin, BRD2, Pumilio 1, Pescadillo, Mre11, NBS1, SERCA2,
AMPK and RFC1. http://www.bethyl.com

        5.2  Reliable Biopharmaceutical Corporation
As the leading U.S. manufacturer of modified nucleic acids, we wanted to
introduce you to our newest product: cis-syn TpT Cyclobutane Dimer
Phosporamidite. Specially developed for the DNA repair and research
markets. You can see our homepage and our TpT Dimer Amidite webpage to
better understand our company and products.
If I or my staff can answer any of your specific questions, please call at
your convenience.

Sincerely,
Sourena Nadji, Ph.D.
Reliable Biopharmaceutical Corporation
Director of Research and Development
(314)429-7700
http://www.reliablebiopharm.com/

        5.3 Novus Biologicals, Inc., Littleton, CO - Antibodies for DNA
Repair Research
(http://www.novus-biologicals.com/research.php/8) and other research
applications (www.novusbio.com). New antibodies include FANCD2, XRCC(2&3),
RAD51(B,C,&D), Tankyrase, DMC-1, DNA polymerase iota, and PAK6.

5.4 Santa Cruz Biotechnology, Inc, Santa Cruz, CA - Antibodies for
research applications.  Please find specific product information at
http://www.scbt.com

        5.5 Austral Biologicals, Inc, San Ramon, CA. - Antibodies for
research applications.
Please visit our web site: http://www.australbio.com




        6       ELECTRONIC CONTACTS:
6.1     Check out the DNA Repair Interest Group web site:
http://www.nih.gov:80/sigs/dna-rep/
You can find the schedule for future DNA Repair Interest Group
videoconferences and a listing of past videoconferences (with links to the
videoarchive) as well as a current list of JOB OPPORTUNITIES in DNA repair
and MEETING NOTICES.

6.2     Encourage your colleagues who are interested in DNA Repair to
request that they be added to this DNA Repair Interest Group listserve
e-mail list by sending a request by e-mail to: listserv at list.nih.gov
Leave the subject  blank. In the message field, type in: subscribe
DNARepair-L your name
        Alternatively, by filling out the form on the website
(http://www.nih.gov:80/sigs/dna-rep/ ) you can both add your name to the
e-mail list and have your name posted on the website.  If you want your
name to be listed you can fill out the "Join the SIG" form on the web site
and add your name to the listing of members.  If you are not at NIH then
be sure to click the "other" box and then fill in the name of your
institution.

6.3     Archives of these listserve mailings can be found at
        http://list.nih.gov/archives/dnarepair-l.html  or via links from
the DNA Repair Interest Group web site:
http://www.nih.gov:80/sigs/dna-rep/

6.4     I will be happy to relay information about post-doctoral
positions, jobs and meetings and other information related to DNA Repair.
Please send me an e-mail message (kraemerk at nih.gov) and I will incorporate
it into the next announcement list and post it on the DNA Repair Interest
Group web site: http://www.nih.gov:80/sigs/dna-rep/ .
(This list goes to more than 950 scientists around the world who are
interested in DNA repair.)


Kenneth H. Kraemer, M.D.
Chief, DNA Repair Section
Basic Research Laboratory
National Cancer Institute
Building 37 Room 3E24
Bethesda,  MD 20892
301-496-9033    FAX: 301-496-8419
e-mail: kraemerk at nih.gov
DNA Repair Interest Group web site:
http://www.nih.gov:80/sigs/dna-rep/


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