FW: DNA Repair Interest Group - UPDATE - October 26, 2003

Charles Miller 4amiller at bellsouth.net
Sun Oct 26 22:20:46 EST 2003


------ Forwarded Message
From: "Kenneth H. Kraemer" <khk at nih.gov>
Reply-To: Ken Kraemer <kraemerk at nih.gov>
Date: Sun, 26 Oct 2003 18:15:54 -0500
To: DNAREPAIR-L at LIST.NIH.GOV
Subject: DNA Repair Interest Group - UPDATE - October 26, 2003

DNA Repair Interest Group - UPDATE - October 26, 2003

1.      VIDEOCONFERENCE -Nov 18, 2003 - Tues 12:30 PM - Dr. Lei Li - Univ
of Texas, M.D. Anderson Cancer Center - DNA Damage Cell Cycle Checkpoint:
Beyond Buying Time for Repair
2.      CONFERENCES -  DNA Repair and Mutagenesis: from Molecular
Structure to Biological Consequences POSTPONED Bermuda; Molecular cross
talk among chromosome fragility syndromes February, 2-4, 2004 Madrid
(Spain); Midwest DNA Repair Symposium, June 5-6, 2004, Lexington, KY;
International Congress of Photobiology June 10-15, 2004, Korea
3.      POST DOC AND EMPLOYMENT OPPORTUNITIES: Baltimore, MD; Research
Triangle Park, NC; Livermore, CA,  Boston, MA; New York, NY; Boston, MA;
Portland, OR; Ontario, Canada; Boston, MA
4.      COMMERCIAL REAGENT SOURCES
5.      Electronic Contacts


1.0     DNA REPAIR VIDEOCONFERENCE:
Nov 18, 2003 - Tues 12:30 PM - Dr. Lei Li - Univ of Texas, M.D. Anderson
Cancer Center - DNA Damage Cell Cycle Checkpoint: Beyond Buying Time for
Repair

VIDEOCONFERENCE LOCATIONS: ; Building 45 (NATCHER) Room H, Bethesda, MD;
Room 1E03 GRC Baltimore, MD Lawrence Livermore Labs, Livermore, CA; Univ
of Michigan, Ann Arbor; University of Pittsburgh; MD Anderson, Smithville,
TX (origin); Building 101 Room B200, NIEHS, Research Triangle Park, NC;
State University of New York, Stony Brook, NY; Univ of Kentucky,
Lexington, KY; Building 549, Conference Room A,  FCRDC, Frederick, MD;
Brookhaven National Labs, Upton, NY; Univ of Texas, Galveston; Oregon
Health & Science University, Portland, OR  [Welcome to our newest site!]
and live on the internet at http://videocast.nih.gov


1.1     DNA REPAIR VIDEOCONFERENCE - FUTURE DATES AND VIDEO ARCHIVE
[Note: A larger and more up to date list of future and past
videoconferences can be found on the DNA Repair Interest Group web site:
http://www.nih.gov:80/sigs/dna-rep/ ]

1.1.1 FUTURE VIDEOCONFERENCES:
Dec 16, 2003 - Tues 12:30 PM - Dr. Andre Nussenzweig - NCI, NIH -The role
of DNA breaks in genomic instability

Jan 20, 2004 - Tues 12:30 PM - Dr. Steve Kowalczykowski -UC Davis -
Biochemistry of Recombinational DNA Repair: Common Themes


Feb 17, 2004 - Tues 12:30 PM - Dr. Dmitry Gordenin -NIEHS, NIH -
Inhibition of mismatch repair by cadmium

Mar 16, 2004 - Tues 12:30 PM - NIH speaker TBA

April 20, 2004 - Tues 12:30 PM - Dr. David Wilson - NIA, NIH - Regulation
of Central Steps in Human Base Excision Repair

May 18, 2004 - Tues 12:30 PM -  Dr. Larry Thompson - Lawrence Livermore
National Lab, Livermore, CA - History of DNA Repair: Chinese hamster cells
and DNA repair - a long-lasting affair

June 15, 2004 - Tues 12:30 PM - Young investigator talks at 3 sites


1.1.2 VIDEOARCHIVES: INTERNET ACCESS (WORLDWIDE):
To date 61 of these videoconferences have been archived and are available
for viewing at your leisure on the internet. You will need a web browser
(with a high speed link) and free Real Video software.  Setup details and
access are available at the NIH videocast website:
http://videocast.nih.gov. Go to Past events; DNA Repair Interest Group
Sessions.

Note: Technical improvements are made regularly on this site to increase
transmission speeds and ease of access. If you were not successful in
viewing these videos in the past it is worth trying again!

Oct 14, 2003-  Dr. Alain Sarasin, Institut Gustave Roussy, Villejuif
France - Xeroderma pigmentosum : Role of the XP variant pol eta gene in
UV-induced mutagenesis.  Toward a gene therapy in XPC patients?

Sept 16, 2003 - Dr. Satya Prakash - Univ of Texas, Galveston -Translesion
synthesis DNA polymerases of yeast and humans

Sept 16 - Dr. Satya Prakash -Studies of human DNA repair diseases in yeast

June 17, 2003 - Dr. John Bradsher, NCI, NIH, Roles of the CS proteins in
Nucleotide Excision Repair and Transcription;

June 17, 2003 - Dr. Tom Rosenquist, SUNY, NEIL proteins and base excision
repair in mice

June 17, 2003 -  Dr. Karen Vasquez, Smithville, TX - Processing of
site-specific DNA lesions by DNA repair and recombination pathways [Note:
The posting of this talk will be delayed at the request of the speaker.]

May 20, 2003 -  Dr. Errol Friedberg, Univ of Texas Southwestern, Dallas,
Tx - Honest Jim Revealed- The Writings of James D. Watson

Apr 15, 2003 - Dr. Qingyi Wei, M.D. Anderson, Houston, Tx - DNA Repair
Function, Polymorphisms and Cancer Risk in the General Population

Mar 11, 2003 - Dr. Sankar Mitra, Univ of Texas, Galveston - Oxidative
Damage Repair and Its Co-ordination in the Mammalian Genome.[Note: The
posting of this talk will be delayed at the request of the speaker.]

March 05, 2003  - Dr. Stephen J. Elledge - Baylor College of Medicine
Houston, TX  - Sensing and Responding to DNA Damage  [Note: this talk was
part of the NIH Wed afternoon lecture series and was sponsored by: the
Mouse Club and Washington Area Yeast Club Interest Group and is now posted
on the DNA Repair Interest Group part of the videocast.nih.gov website.]

Jan 21, 2003 - Tues 12:30PM - Dr. Jack Taylor, NIEHS - Epidemiologic
studies of DNA repair gene polymorphisms and cancer risk

Dec 17, 2002 - Dr. John Tainer, UC Berkeley - Conformational Controls and
DNA Repair Coordination - [Note: The posting of this talk will be delayed
at the request of the speaker.]

Nov 12, 2002 - Dr. Rob Sobol, Univ of Pittsburgh - DNA Base Damage and
Repair Intermediates: Out of the Pan and into the Fire

Oct 15, 2002 - Dr. Al Fornace, NCI - Convergence of the p53 and MAP kinase
stress signaling pathways after UV radiation

Sept 17, 2002 - Dr. Dale Ramsden, UNC - DNA Double strand break repair

June 18, 2002 - Dr. David Chen - Lawrence Berkeley National Lab - Role of
DNA-PK in Cellular Responses to DNA damage

May 21, 2002 -  Dr. Mark J. Schofield - NIH, Bethesda - DNA mismatch
repair; Dr. Sunitha Yanamadala - Univ of Michigan - Role of Mismatch
Repair Proteins in Signaling p53 and Apoptosis; Dr. Federica Marini - Univ
of Pittsburgh - A human DNA helicase homologous to the DNA crosslink
sensitivity protein mus308

Apr 16, 2002 -  Dr. Philip Hanawalt - Half a century of DNA repair: An
historical perspective

Mar 19, 2002 - Dr. Alan Tomkinson - Univ of Texas, San Antonio -
Mechanisms of DNA End Joining

Feb 19, 2002 - Dr. Yves Pommier - NCI - Nucleotide excision
repair-dependent cytotoxicity of a novel anticancer agent, ecteinascidin
743

Jan 15, 2002 - Dr. Tom Kunkel- NIEHS - Recent studies of DNA Mismatch
Repair

Through the miracle of videotape we now have been able to post most of the
DNA Repair Interest Group videoconferences from 1998,1999, 2000 and 2001
on the web site.  These include talks by Drs. Anderson, Beernik,
Bogenhagen, Bohr, Brash, Brooks, Brosh, Chu, Cleaver, Copeland,
Drotschmann, Emmert, Essigman, Fornace, George, Glazer, Grossman,
Hanawalt, Jin, Kashlev, Kraemer, Kunkel, Leadon, Liu, Ljungman, Matson,
Matsumoto,  McKay,  Setlow, Sharan, Sobol, States, Stefanini, Sung,
Sutherland, Thompson, Wang, Wood, Woodgate and Yarosh.


2.    CONFERENCES -  DNA Repair and Mutagenesis: from Molecular Structure
to Biological Consequences POSTPONED Bermuda; Molecular cross talk among
chromosome fragility syndromes February, 2-4, 2004 Madrid (Spain); Midwest
DNA Repair Symposium, June 5-6, 2004, Lexington, KY;  International
Congress of Photobiology June 10-15, 2004, Korea
[Note: A larger and more up-to-date list of conferences can be found on
the DNA Repair Interest Group web site:
http://www.nih.gov:80/sigs/dna-rep/ ]

2.1  DNA REPAIR AND MUTAGENESIS: FROM MOLECULAR STRUCTURE TO BIOLOGICAL
CONSEQUENCES - BERMUDA, DECEMBER 7-13, 2003. [POSTPONED] NOTE: THIS
CONFERENCE HAS BEEN POSTPONED UNTIL NOV 14-20, 2004 BECAUSE OF HURRICANE
DAMAGE TO THE HOTEL IN BERMUDA.  SEE THE WEBSITE FOR MORE DETAILS.

Dear Colleagues,
We are writing to let you know that we will be organizing an ASM
Conference entitled "DNA Repair and Mutagenesis: From Molecular Structure
to Biological Consequences" sponsored by the American Society for
Microbiology to be held at the Fairmont Southampton Princess, Bermuda,
December 7-13, 2003. The conference will bring together the various
subdisciplines that collectively comprise the field of DNA Repair and
Mutagenesis. Meetings of this type have been held at approximately four
year intervals since 1974, the preceding one in this informal series
having been at Hilton Head, South Carolina in 1999, and have played a
critical role in the development of this exciting area of research.

Speakers will include: Genevive Almouzni, Lorena Beese, Serge Boiteux,
Jaap Brouwer, Keith Caldecott, Judith Campisi, Gilbert Chu, Priscilla
Cooper, Titia de Lange, John Diffley, Sylvie Doubli, Jean-Marc Egly,
Stephen Elledge, Tom Ellenberger, Rick Fishel, Marco Foiani, Errol
Friedberg, Robert Fuchs, James Haber, Fumio Hanaoka, Phil Hanawalt, Jan
Hoeijmakers, Peggy Hsieh, Ian Hickson, Stephen Jackson, Maria Jasin, Penny
Jeggo, Joe Jiricny, Roland Kanaar, Richard Kolodner, Stephen
Kowalczykowski, Thomas Kunkel, Tony Leadon, Alan Lehmann, Tomas Lindahl,
Bndicte Michel, Sankar Mitra, Paul Modrich, Leon Mullenders, Tanya Paull,
John Petrini, Louise Prakash, Miroslav Radman, Rodney Rothstein, Leona
Samson, Alain Sarasin, Erling Seeberg, Jesper Svejstrup, John Tainer,
Shunichi Takeda, Kiyoji Tanaka, Graham Walker, Susan Wallace, Stephen
West, Sam Wilson, Richard Wood, Roger Woodgate, and Wei Yang.
Some additional speakers on timely topics will be invited closer to the
date of the meeting, and furthermore, speakers will be chosen from among
the submitted abstracts for shorter presentations.

Careful thought has been given to the choice of the site and the design of
the program so that participants will be able to enjoy the type of
opportunities for informal discussions and interactions that are normally
found only at smaller meetings. A special feature of the meeting will be
travel grants to help support the participation of graduate students and
postdoctoral fellows. Additional information concerning the meeting and
the program is available at:
http://www.asm.org/Meetings/index.asp?bid=1137
We hope you will mark these dates on your calendars. We look forward to
seeing you in Bermuda in December 2003!

Best Wishes
Graham Walker, Susan Wallace, and Priscilla Cooper


2.2 MOLECULAR CROSS TALK AMONG CHROMOSOME FRAGILITY SYNDROMES
2-4 February, 2004. Madrid (Spain)

Scientific Organizers:
Hans Joenje, Department of Clinical Genetics and Human Genetics, Free
University Medical Centre, Amsterdam
Jordi Surralles, Department of Genetics and Microbiology, Universitat
Autonoma de Barcelona, Barcelona, Spain

Format:
The workshop will consist of lectures and poster sessions; there will be
extended time for formal and informal discussion. Some posters may be
selected for presentation as short talks.

Invited speakers (all confirmed):
A. Ashworth (London, UK)
M. A. Blasco (Madrid, Spain)
P. Concannon (Seattle, WA. USA)
A. D. D'Andrea (Boston, MA. USA)
S. P. Jackson (Cambridge, UK)
M. Jasin (New York, NY. USA)
P. A. Jeggo (Brighton, UK)
H. Joenje (Amsterdam, The Netherlands)
R. Kanaar (Rotterdam, The Netherlands)
M. B. Kastan (Memphis, TN. USA)
A. Nussenzweig (Bethesda, MD. USA)
K. J. Patel (Cambridge, UK)
J. H. J. Petrini (New York, NY. USA)R. Scully (Boston, MA. USA)
Y. Shiloh (Tel Aviv, Israel)
J. Surralles (Barcelona, Spain)
S. Takeda (Kyoto, Japan)
A. M. R. Taylor (Birmingham, UK)
H. Te Riele (Amsterdam, The Netherlands)
A. Venkitaraman (Cambridge, UK)
S. C. West (Herts, UK)
M. Z. Zdzienicka (Al Leiden, The Netherlands)

Programme: The human genome has evolved a number of cellular mechanisms in
response to chromosome breaks to counteracts the mutational load and
prevent tumour transformation. Consequently, defects in these mechanisms
increase cancer risk and lead to chromosome fragility cancer-prone
syndromes such as Fanconi anemia (FA), ataxia telangiectasia (AT),
Nijmegen breakage syndrome (NBS), and several types of hereditary breast
cancer with mutation in the BRCA1/BRCA2 genes.  Therefore, basic research
on these syndromes is particularly interesting not only to find a cure for
the patients but also to understand key biological processes required to
maintain the genome stability and prevent cancer in the general
population. The following topics will be discussed: 1) Nijmegen breakage
syndrome and the Mre11-Rad50-NBS1 complex; 2) Ataxia telangiectasia and
downstream effectors; 3) Fanconi anemia and its cross talk with DSB repair
proteins; 4) BRCA proteins and double strand break repair networking; 5)
Cellular response to chromosome breaks.

For all requests, please go to the web site: http://www.march.es and then
link to Centre for International Meetings on Biology

Greetings and see you in Madrid
Jordi Surralles

2.3 The 6th Annual Midwest DNA Repair Symposium, June 5-6, 2004,
Lexington, KY

Dear Colleagues,
We will be holding The 6th Annual Midwest DNA Repair Symposium in
Lexington, KY from June 5-6 (Sat.-Sun.), 2004. Rick Wood has agreed to be
one of our keynote speakers. As in the past, most speakers/poster
presentations will be selected from submitted abstracts. Please consider
joining us. A website providing more detailed information will be created
in the future. The local organizing committee also includes Guo-Min Li,
Zhigang Wang, David Orren, Liya Gu, Andy Pierce, and Isaac Wong. We hope
that you will circulate this among your colleagues and consider joining us
next June.

Best Regards, Isabel Mellon




2.4 INTERNATIONAL CONGRESS ON PHOTOBIOLOGY - JEJU ISLAND, KOREA - JUNE
10-15, 2004.

The 14th International Congress on Photobiology sponsored by the
International Union of Photobiology and hosted by the Korean Society of
Photoscience, Photobiology Association of Japan, and Asia and Oceania
Society for Photobiology will be held June 10-15, 2004, on the island of
Jeju, Korea. Both Korean Society of Photoscience, Korean Photodynamic
Association, and Asia and Oceania Society for Photobiology will also hold
their annual meetings in conjunction with the Congress at the same time.
More details can be found at:
http://photos.or.kr/ICP2004 (ICP is case-sensitive)

I would like to invite you to register to participate in the Congress by
visiting the website and filling out the registration form therein. To
make the Congress successful, your suggestions and contributions are
essential and will be greatly appreciated by the Organizing Committee. In
order to make the Congress scientifically attractive, we plan to organize
nearly 50 symposia and 10 special lectures. In addition, we are planning
to present a national photobiology-society sponsored Plenary Lecture each
day of the
Congress.

The Congress venue is the Island of Jeju. It is one of the most beautiful
islands in the world. It offers many sightseeing and leisure attractions.
Bring your family and friends. You will enjoy it.

See you all here in Jeju, Korea, in Year 2004!

Best wishes,
Pill-Soon Song
Congress President-ICP2004


3.      POST DOC AND EMPLOYMENT OPPORTUNITIES: Research Triangle Park, NC;
Livermore, CA,  Boston, MA; New York, NY; Boston, MA; Portland, OR;
Ontario, Canada; Boston, MA  [Note: Check the list for more Job
Opportunities on the DNA Repair Interest Group web site:
http://www.nih.gov:80/sigs/dna-rep/ ]


3.1 NIH POSTDOCTORAL POSITION - GENOME STABILITY - RESEARCH TRIANGLE PARK,
NC
NIH POSTDOCTORAL POSITION to investigate highly relevant genome stability
issues using yeast and/or human cell systems.  Research projects are
available in several related directions that include i) DNA double-strand
breaks (origin, repair, recombination, replication, cell signaling, and
real time analysis); ii) replication and mutation avoidance; iii)
influence of mitochondria on genome stability; and iv) human p53 function,
role in genome stability and model for evolution of regulatory networks
(see http://dir.niehs.nih.gov/dirlmg/home.htm).  A variety of genetic,
molecular, and functional genomics approaches are used that have been
developed in this Section. Along with exceptional facilities and
resources, the Section provides a highly interactive and unique scientific
environment with several areas of expertise, so as to create an
exceptional training opportunity.
The Section is part of the Laboratory of Molecular Genetics (LMG) with
many PI's renowned for their contributions to the area of genome stability
and is located at the National Institute for Environmental Health Sciences
(NIEHS) of the NIH.  NIEHS is in a highly attractive area of North
Carolina that is central to prominent research institutions.  A unique
feature of the postdoctoral program is the opportunity to apply for
special grants for subsequent tenure-track academic appointments. Salary
and benefits are competitive.
Application.  Send CV & names of references to Dr. Michael Resnick, Head,
Chromosome Stability Section, NIEHS, P.O. Pox 12233, Research Triangle
Park, NC  27709; resnick at niehs.nih.gov


        3.2 POST-DOCTORAL FELLOWSHIP - OXIDATIVE DAMAGE - LIVERMORE, CA
A California Breast Cancer Research Program-funded postdoctoral fellowship
is available to study the role of DNA oxidation in breast tumor
progression. In particular, the laboratory is interested in assaying for
the in vivo oxidation products of 7,8-dihydro-8-oxo-2'-deoxyguanine, a
known DNA damage product in breast cells. The hypothesis is that these
products play a role in tumor initiation and progression towards
malignancy. Experience in molecular and cell biology using radiolabeled
probes is desired. Salary: $40,000-55,000. Please send resume to: Dr. Paul
Henderson, L-441, Biology and Biotechnology Research Program, Lawrence
Livermore National Laboratory, Livermore, CA 94551. e-mail:
henderson48 at llnl.gov

        3.3 POSTDOCTORAL POSITION - HOMOLOGOUS RECOMBINATION - CAMBRIDGE,
MA

Postdoctoral position - Biological Engineering Division, Massachusetts
Institute of Technology, Cambridge, MA. A postdoctoral position is
available in the laboratory of Bevin P. Engelward to develop novel
transgenic mouse systems for measuring mitotic homologous recombination
via fluorescence detection within tissues, and to study interactions
between DNA excision repair and homologous recombination in eukaryotes.
Experience in genetics, molecular biology, cell biology, DNA repair, or
knockout/transgenic mouse technology is desired. Interested individuals
should send their C.V., a description of their research experience and
interests, and the names of three references to:

Bevin P. Engelward, Sc.D.
Associate Professor of Biological Engineering
MIT Biological Engineering Division, 56-631
77 Massachusetts Avenue
Cambridge, MA 02139
        http://web.mit.edu/bevin/www/

MIT is an Equal Opportunity/Affirmative Action Employer

        3.4 POST DOCTORAL POSITION - COLUMBIA UNIVERSITY, NEW YORK
A postdoctoral position is available immediately at the Department of
Radiation Oncology, Center for Radiological Research, Columbia University
to pursue studies of signal transduction pathway(s) involved in radiation
induced DNA damage and bystander response in mammalian cells. Candidate
with a recent a Ph.D. degree in Biochemistry, Molecular biology or Cell
biology is required. Experience in cell culture, protein biochemistry and
signal transduction research experience is preferred.
Interested candidates can submit their resume, areas of research interests
and three letters of recommendations to either
Prof. Charles R. Geard or Dr. A.S. Balajee
Department of Radiation Oncology
Center for Radiological Research
College of Physicians and Surgeons
Columbia University, VC-11, Room 243
168th Street, 630 West
New York, NY 10032.
Informal enquiries can be made to Dr. A.S. Balajee (ab836 at columbia.edu).

        3.5 POSTDOCTORAL POSITION - ALKYLATION DAMAGE - BOSTON, MA
Postdoctoral position - Biological Engineering Division Massachusetts
Institute of Technology, Boston, MA.  A postdoctoral position is available
in the lab of Leona D. Samson to study the biological effects of
alkylation damage.  Research areas include: (1) exploring the molecular
basis of cellular signaling in response to DNA alkylation damage; (2)
alkylation damage-induced global transcriptional responses; (3) functional
genomic approaches (genomic phenotyping) to identifying novel recovery
pathways; (4) transgenic and knockout mice to study the influence of
alkylation damage on apoptosis, mutation, genome stability and
tumorigenesis; (5) gene therapy approaches to suppressing bone marrow
toxicity.  Experience in biochemistry, molecular biology, cell biology,
DNA repair, or knockout/transgenic mouse technology is desired.
Selected Publications:
Hickman, M. and Samson, L.D. (1999) Role of DNA mismatch repair and p53 in
signaling induction of apoptosis by alkylating agents. Proc. Natl. Acad.
Sci., 96: 10764-10769.
Roth, R.B., and Samson, L.D. (2000) Gene transfer to suppress bone marrow
alkylation toxicity.  Mutation Research, 462:107-120.
Lau, A.Y., Wyatt, M.D., Glassner, G., Samson, L.D., and Ellenberger, T.E.
(2000) Molecular basis for discriminating between normal and damaged bases
by the human alkyladenine glycosylase, AAG. Proc. Natl. Acad. Sci,
97(25):13573-13578.
Jelinsky, S., Estep, P., Church, G., and Samson, L. D. (2000) Regulatory
networks revealed by transcriptional profiling of damaged Saccharomyces
cerevisiae cells:  Rpn4 links base excision repair with proteasomes,
Molecular and Cellular Biology, 20 (21):8157-8167.
 Roth, R. and Samson, L.D. (2002) 3-methyladenine DNA
glycosylase-deficient Aag null mice display unexpected bone marrow
alkylation resistance, Cancer Research 62, 656-660.
Begley, T.J., Rosenbach, A.S., Ideker, T. and Samson, L.D. (2002) Recovery
Pathways in S. cerevisiae Revealed by Genomic Phenotyping and Interactome
Mapping, Molecular Cancer Research, in press
Begley T.J. and Samson, L.D. (2003) AlkB mystery solved:  Oxidative
demethylation of N1-methyladenine and N3-methylcytosine adducts by a
direct reversal mechanism, Trends in the Biochemical Sciences, in press

Please send CV and 3 letters of Reference to:
Leona D. Samson
Ellison American Cancer Society Research Professor
Biological Engineering Division, and
Director of the Center for Environmental Health Sciences
Massachusetts Institute of Technology
77 Massachusetts Avenue, 56-235
Cambridge, MA 02139
or via email: lsamson at mit.edu

        3.6 POSTDOCTORAL POSITION-NERVOUS SYSTEM DNA REPAIR, PORTLAND, OR
A postdoctoral position is available immediately to study the role of DNA
damage and DNA repair in the nervous system. Particular emphasis is on
understanding the role of BER and NER in maintaining the integrity of
neurons and other cell types of the central nervous system. Currently
funded projects involve the use of whole animal and cell culture models
from transgenic/knockout DNA repair mutant mice to explore the
relationship between neuronal cell death and DNA damage during development
and in age-related neurodegenerative disease (e.g., Parkinson's,
Alzheimer's, and Lou Gehrig's disease). PhD candidates (less than 5 yrs
experience) with a strong background in molecular or cell biology and DNA
repair and experience in mammalian cell culture, protein biochemistry,
gene expression, protein-protein interaction, DNA microarrays are
encouraged to apply.

For more information, send an email to the address below. To apply, please
send your C.V., a description of your research experience, and the names,
addresses, telephone numbers and email addresses of three references to:


Glen Kisby, PhD
Associate Professor
Ctr for Res on Occup
& Environ Toxicol (CROET)
Oregon Health & Science University (OHSU)
3181 SW Sam Jackson Park Rd
Portland, OR 97201-3098E-mail: kisby at ohsu.edu

Portland is an affordable centrally located city in the beautiful state of
Oregon. The University is only 1 h away from year round skiing at Mt Hood,
the Pacific Ocean, and the scenic deserts of eastern Oregon. The campus
contains a large group of distinguished faculty with special emphasis on
the nervous system. CROET is a unique research institute with faculty that
conduct applied research in the workplace (i.e., epidemiology) and basic
research at the cellular and molecular level.

3.7 POSTDOCTORAL POSITION IN MAMMALIAN DNA REPAIR DEPARTMENT OF BIOLOGY,
McMASTER UNIVERSITY, ONTARIO, CANADA

A postdoctoral position is available immediately to study the DNA repair
pathways in mammalian cells. Our laboratory is particularly interested in
the mechanisms of inducible DNA repair pathways following exposure to UVA,
UVB and UVC and how deficiencies in DNA repair play a role in human
disease. Research areas include the role of several human ERCC genes in
inducible DNA repair as well as several aspects of the DNA repair
deficiency in cells from patients with xeroderma pigmentosum, Cockayne
syndrome, Li-Fraumeni syndrome and ataxia telangiectasia. Our laboratory
has developed a number of techniques to study DNA repair using
adenoviruses as probes and expression vectors and the application of these
techniques to other areas of mammalian DNA repair are also possible
research areas in my laboratory.

The position is initially for one year (minimum starting salary of
$30,000) with the possibility of extension for two further years.
Candidates with a recent Ph.D., a background in cell biology, molecular
biology and genetics, some experience in mammalian cell culture and a good
knowledge of both written and spoken English are encouraged to apply.
Please send a CV and the names and addresses (including email address and
telephone number) of three references to:

Andrew J. Rainbow, Ph.D.
Department of Biology
McMaster University
Hamilton, Ontario L8S 4K1
Canada.

Telephone: (905)-525-9140, ext. 23544
Fax: (905)-522-6066
Email: rainbow at mcmaster.ca
Website:
http://www.science.mcmaster.ca/biology/faculty/rainbow/rainbow.htm

        3.8 POSTDOCTORAL/RESEARCH ASSOCIATE POSITIONS - BOSTON
Two openings available immediately to study the role of AP endonuclease in
the cell physiology and biochemistry of DNA base excision repair.  We are
a dynamic group in a young department with lots of opportunity.  The
successful candidate will be smart, enterprising and hard working.  We
need you!
Contact:  Phyllis Strauss, Northeastern University, Boston MA 02115,
e-mail: p.strauss at neu.edu.



        4.0  COMMERCIAL REAGENT SOURCES
[Note: There are more commercial reagent sources listed on the DNA Repair
interest group website: http://www.nih.gov:80/sigs/dna-rep/    These
sources are listed as a convenience to our readers and do not constitute
an endorsement of any of these companies or their products.]

        4.1 Bethyl Laboratories, Inc. - Antibodies for DNA Damage/Repair
and related research (www.bethyl.com)  New antibodies include SDS3, DMAP1,
KIF14, DIS, MCM2, MCM3, MCM4, MCM6, MCM7, MCM10, Claspin, BRD2, Pumilio 1,
Pescadillo, Mre11, NBS1, SERCA2, AMPK and RFC1. http://www.bethyl.com

        4.2  Reliable Biopharmaceutical Corporation - As the leading U.S.
manufacturer of modified nucleic acids, we wanted to introduce you to our
newest product: cis-syn TpT Cyclobutane Dimer Phosporamidite. Specially
developed for the DNA repair and research markets. You can see our
homepage and our TpT Dimer Amidite webpage to better understand our
company and products.

If I or my staff can answer any of your specific questions, please call at
your convenience.

Sincerely,
Sourena Nadji, Ph.D.
Reliable Biopharmaceutical Corporation
Director of Research and Development
(314)429-7700
http://www.reliablebiopharm.com/

        4.3 Novus Biologicals, Inc., Littleton, CO - Antibodies for DNA
Repair Research (http://www.novus-biologicals.com/research.php/8) and
other research applications (www.novusbio.com). New antibodies include
Rad9, HLTF, Aurora A and B, XAGE, chk1, and phosphorylated proteins
(mNBS1, hNBS1, SMC-1 and 3, BRCA1, Rad17, and chk1).  For more information
contact:


Bryan Tinsley
Novus Biologicals, Inc.
5951 S. Middlefield Rd. Suite 103
Littleton, CO 80123
303-730-1950
fax: 303-730-1966
bryan at novusbio.com
Visit our website for the most up to date product listings
www.novusbio.com

4.4 Santa Cruz Biotechnology, Inc, Santa Cruz, CA - Antibodies for
research applications.  Please find specific product information at
http://www.scbt.com

        4.5 Austral Biologicals, Inc, San Ramon, CA. - Antibodies for
research applications.
Please visit our web site: http://www.australbio.com


        5       ELECTRONIC CONTACTS:
5.1     Check out the DNA Repair Interest Group web site:
http://www.nih.gov:80/sigs/dna-rep/
You can find the schedule for future DNA Repair Interest Group
videoconferences and a listing of past videoconferences (with links to the
videoarchive) as well as a current list of JOB OPPORTUNITIES in DNA repair
and MEETING NOTICES.

5.2     Encourage your colleagues who are interested in DNA Repair to
request that they be added to this DNA Repair Interest Group listserve
e-mail list by sending a request by e-mail to: listserv at list.nih.gov
Leave the subject  blank. In the message field, type in: subscribe
DNARepair-L your name
        Alternatively, by filling out the form on the website
(http://www.nih.gov:80/sigs/dna-rep/ ) you can both add your name to the
e-mail list and have your name posted on the website.  If you want your
name to be listed you can fill out the "Join the SIG" form on the web site
and add your name to the listing of members.  If you are not at NIH then
be sure to click the "other" box and then fill in the name of your
institution.

5.3     Archives of these listserve mailings can be found at
        http://list.nih.gov/archives/dnarepair-l.html  or via links from
the DNA Repair Interest Group web site:
http://www.nih.gov:80/sigs/dna-rep/

5.4     I will be happy to relay information about post-doctoral
positions, jobs and meetings and other information related to DNA Repair.
Please send me an e-mail message (kraemerk at nih.gov) and I will incorporate
it into the next announcement list and post it on the DNA Repair Interest
Group web site: http://www.nih.gov:80/sigs/dna-rep/ .
(This list goes to more than 1050 scientists around the world who are
interested in DNA repair.)


Kenneth H. Kraemer, M.D.
Chief, DNA Repair Section
Basic Research Laboratory
National Cancer Institute
Building 37 Room 3E24
Bethesda,  MD 20892
301-496-9033    FAX: 301-496-8419
e-mail: kraemerk at nih.gov
DNA Repair Interest Group web site:
http://www.nih.gov:80/sigs/dna-rep/


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