[Toxicology] Fwd: DNA Repair Interest Group - UPDATE - June 21, 2005

Charles Miller rellim at tulane.edu
Tue Jun 21 19:57:49 EST 2005



Begin forwarded message:

> From: "Kenneth H. Kraemer" <khk at NIH.GOV>
> Date: June 21, 2005 6:17:14 PM CDT
> To: DNAREPAIR-L at LIST.NIH.GOV
> Subject: DNA Repair Interest Group - UPDATE - June 21, 2005
> Reply-To: Ken Kraemer <kraemerk at NIH.GOV>
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>
> DNA Repair Interest Group - UPDATE - June 21, 2005
>
> 1 - VIDEOCONFERENCE:     On vacation for the summer.
>
> 2 - NIH SEMINARS OF NOTE: June 23 Thu 11:00 AM - Dr. Richard Kolodner
> "Identification of pathways that prevent genome instability".   
> Location:
> Building 50 Room 1227.
>
> 3 - CONFERENCES -  GORDON RESEARCH CONFERENCE ON GENETIC TOXICOLOGY -
> COLBY-SAWYER, NEW LONDON, NH - JULY 31ST-AUGUST 5TH 2005;   
> INTERNATIONAL
> MEETING ON O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE (MGMT). AUGUST 6-9,  
> 2005,
> KEELE CONFERENCE PARK, UK;  STRUCTURAL BIOLOGY OF DNA REPAIR- AUG 28 -
> SEPT 1, 2005; CELL LINEAGES, GENETIC INSTABILITY AND HUMAN DISEASE  
> AUGUST
> 31-SEPTEMBER 2, 2005, SEATTLE, WA;  9TH INTERNATIONAL CONFERENCE ON
> ENVIRONMENTAL MUTAGENS - SEPT 3-8, 2005 - SAN FRANCISCO; 11TH  
> CONGRESS OF
> THE EUROPEAN SOCIETY FOR PHOTOBIOLOGY AIX-LES-BAINS, FRANCE,  
> SEPTEMBER 3 -
> 8, 2005;  RESPONSES TO DNA DAMAGE: INSIGHTS FROM CHEMICAL,  
> BIOCHEMICAL,
> STRUCTURAL BIOLOGY AND CELLULAR STUDIES 19-21 SEPTEMBER 2005,  
> BRIGHTON,
> UK; US-EU WORKSHOP "SYSTEMS LEVEL UNDERSTANDING OF DNA DAMAGE  
> RESPONSES"
> SEPTEMBER 30-OCTOBER 4, 2005, STOWE, VERMONT, USA; 5TH  
> INTERNATIONAL 3R
> SYMPOSIUM NOVEMBER 13-17, 2005, - AWAJI YUMEBUTAI INTERNATIONAL  
> CONFERENCE
> CENTER, AWAJI ISLANDS, HYOGO, JAPAN
>
> 4- POST DOC AND EMPLOYMENT OPPORTUNITIES: Bethesda, MD;  
> Indianapolis, IN;
> Buffalo, NY; Columbia, S.C.; Worcester, MA; Burlington, VT,  
> Rochester, MN;
> London, UK
>
> 5 - COMMERCIAL REAGENT SOURCES
>
> 6 - ELECTRONIC CONTACTS
>
>
> 1.0     DNA REPAIR VIDEOCONFERENCE:     On vacation - will resume  
> in the
> summer
>
> VIDEOCONFERENCE LOCATIONS:  Building 45 (NATCHER) Room J, Bethesda, MD
> (origin); Room 1E03 GRC Baltimore, MD; Lawrence Livermore Labs,  
> Livermore,
> CA; Univ of Michigan, Ann Arbor; University of Pittsburgh; MD  
> Anderson,
> Smithville, TX; Building 101 Room B200, NIEHS, Research Triangle  
> Park, NC
> State University of New York, Stony Brook, NY; Univ of Kentucky,
> Lexington, KY; Building 549, Conference Room A,  FCRDC, Frederick, MD;
> Brookhaven National Labs, Upton, NY; Oregon Health & Science  
> University,
> Portland, OR; Univ of North Carolina, Chapel Hill, NC and live on the
> internet at http://videocast.nih.gov
>
>
> 1.1     DNA REPAIR VIDEOCONFERENCE - FUTURE DATES AND VIDEO ARCHIVE
> [Note: A larger and more up to date list of future and past
> videoconferences can be found on the DNA Repair Interest Group web  
> site:
> http://www.nih.gov:80/sigs/dna-rep/ ]
>
> 1.1.1 FUTURE VIDEOCONFERENCES:
>
> TBA
>
> 1.1.2 VIDEOARCHIVES: INTERNET ACCESS (WORLDWIDE):
> To date 84 of these videoconferences have been archived and are  
> available
> for viewing at your leisure on the internet. You will need a web  
> browser
> (with a high speed link) and free Real Video software.  Setup  
> details and
> access are available at the NIH videocast website:
> http://videocast.nih.gov. Go to Past events; DNA Repair Interest Group
> Sessions.
>
> Note: Technical improvements are made regularly on this site to  
> increase
> transmission speeds and ease of access. If you were not successful in
> viewing these videos in the past it is worth trying again.   We  
> recently
> received a log of the use of these videocasts. They were downloaded  
> nearly
> 10,000 times in the past two years!
>
> June 14, 2005 - Dr. Kurt W. Kohn, NCI - A personal history of DNA  
> damage
> and repair research 1960-2005 [Note: Adobe Acrobat files with  
> slides from
> this talk can be downloaded at this site.]
>
> May 18 - Dr. Steve West - Cancer Research, UK also gave a lecture  
> in the
> NIH Director.s Wed Afternoon lecture series Title:  Making Ends Meet:
> Double-strand Break Repair in Human Cells
>
> May 17, 2005 - Dr. Steve West - Cancer Research UK, London Research
> Institute - Title: New insights into mechanisms of BRCA2-regulated
> double-strand break repair
> [Note: Adobe Acrobat files with slides from this talk can be  
> downloaded at
> this site. The posting of the video is delayed at the request of the
> speaker]
>
> April 19, 2005 - Short talks by young investigators:
> Dr. Miguel Garcia-Diaz - NIEHS - Structural analysis of strand
> misalignment during DNA synthesis; [Note: Adobe Acrobat files with  
> slides
> from this talk can be downloaded at this site. The posting of the  
> video is
> delayed at the request of the speaker]
>
> Dr. Kyungjae Myung - NHGRI -Suppression and formation of gross  
> chromosomal
> rearrangements through cross talk between different DNA metabolisms;
> [Note: Adobe Acrobat files with slides from this talk can be  
> downloaded at
> this site. The posting of the video is delayed at the request of the
> speaker]
>
> Dr. John Hinz - Livermore, CA -Distinct genomic instabilities  
> associated
> with deficiencies in homologous recombination or the Fanconi anemia  
> FANCD2
> monoubiquitination pathway [Note: The posting of the video is  
> delayed at
> the request of the speaker]
>
> March 15, 2005 - Dr. Wei Yang - NIDDK - DNA repair in 3D.  [Note:  
> Adobe
> Acrobat files with slides from this talk can be downloaded at this  
> site.
> The posting of the video is delayed at the request of the speaker]
>
> Feb 16, 2004 Dr. Judy Campisi also gave a lecture in the NIH  
> Director.s
> Wed Afternoon lecture series on the following day. Title: Cancer and
> aging: Rival demons?
>
> Feb 15, 2005 - Dr. Judy Campisi - Univ of California Berkeley - Title:
> Genome maintenance systems, cancer and aging  [Note: Adobe Acrobat  
> files
> with slides from this talk can be downloaded at this site. The  
> posting of
> the video is delayed at the request of the speaker]
>
> Jan 18, 2005 - Dr. Michael Seidman - NIA - Repair and Mutagenesis of
> Triplex Targeted Interstrand Crosslinks. [Note: Adobe Acrobat files  
> with
> slides from this talk can be downloaded at this site. The posting  
> of the
> video is delayed at the request of the speaker]
>
>
> Dec 21, 2004 - Tues 12:30 PM - Dr. Thomas Wilson - Univ of Michigan
> -Nonhomologous end-joining: lessons from yeast.  Origin of
> Videoconference: Univ of Michigan  [Note: Adobe Acrobat files with  
> slides
> from this talk can be downloaded at this site. The posting of the  
> video is
> delayed at the request of the speaker]
>
> Nov 16, 2004 - Dr. Susan Olson - OHSU, Portland, OR - Exploring  
> Cellular
> and Molecular Aspects of Fanconi Anemia from a Cytogenetic Perspective
> [Note: The posting of this talk is delayed at the request of the  
> speaker]
>
> Oct 19, 2004 - Dr. Roel Schaaper - NIEHS- Novel mutators and the
> correction of replication errors in E. coli  [Note: The posting of  
> this
> talk is delayed at the request of the speaker]
>
> Sept 21, 2004 - Dr. Ken Kraemer -Clinical, Molecular and Epidemiologic
> Studies of Xeroderma Pigmentosum and Related Disorders of DNA Repair
> [Note: Adobe Acrobat files with slides from this talk can be  
> downloaded at
> this site.]
>
> June 15, 2004 -Young investigator showcase:  Dr. Sikandar Khan -  
> NCI - Two
> Essential Splice Lariat Branchpoint Sequences in One Intron in a  
> Xeroderma
> Pigmentosum DNA Repair Gene [Note: Adobe Acrobat files with slides  
> from
> this talk can be downloaded at this site.]
>
> June 15, 2004 -Young investigator showcase: Dr. Francesca Storici -  
> NIEHS
> - Addressing Mechanisms of Recombination and Double Strand Break  
> Repair in
> Yeast with Targeted Oligonucleotides and the Delitto Perfetto Approach
> [Note: Adobe Acrobat files with slides from this talk can be  
> downloaded at
> this site.]
>
> June 15, 2004 -Young investigator showcase: Dr. Diane Cabelof - Wayne
> State, Detroit - Induction of Spontaneous Tumors in beta-pol
> Haploinsufficient Mice [Note: The posting of this talk is delayed  
> at the
> request of the speaker]
>
> May 18, 2004 - Dr. Larry Thompson - Lawrence Livermore National Lab,
> Livermore, CA - History of DNA Repair: Chinese Hamster Cells and DNA
> Repair - A Long-Lasting Affair [Note: An Adobe Acrobat file with  
> slides
> from this talk can be downloaded at this site. The posting of the  
> video of
> this talk will be delayed at the request of the speaker.]
>
> April 20, 2004 - Dr. David Wilson - NIA, NIH - Regulation of  
> Central Steps
> in Human Base Excision Repair  [Note: An Adobe Acrobat file with  
> slides
> from this talk can also be downloaded at this site.]
>
> Mar 16, 2004 -Dr. Alan Lehmann - Brighton, UK - Translesion  
> Synthesis and
> Polymerase Switching in Human Cells
>
> Feb 17, 2004 - Dr. Dmitry Gordenin - NIEHS- Inhibition of Mismatch  
> Repair
> by Cadmium [Note: An Adobe Acrobat file with slides from this talk can
> also be downloaded at this site.]
>
> Jan 20, 2004  - Dr. Steve Kowalczykowski - Biochemistry of  
> Recombinational
> DNA Repair: Common Themes [Note: An Adobe Acrobat file with slides  
> from
> this talk can also be downloaded at this site.]
>
> Dec 16, 2003  - Dr. Andre Nussenzweig - Experimental Immunology  
> Branch,
> CCR, NCI, NIH -The Role of DNA Breaks in Genomic Instability
>
> Nov 18, 2003 - Dr. Lei Li - Univ of Texas, M.D. Anderson Cancer  
> Center -
> DNA Damage Cell Cycle Checkpoint: Beyond Buying Time for Repair
>
> Oct 14, 2003-  Dr. Alain Sarasin, Institut Gustave Roussy, Villejuif
> France - Xeroderma pigmentosum : Role of the XP variant pol eta  
> gene in
> UV-induced mutagenesis.  Toward a gene therapy in XPC patients?
>
> Sept 16, 2003 - Dr. Satya Prakash - Univ of Texas, Galveston - 
> Translesion
> synthesis DNA polymerases of yeast and humans
>
> Sept 16, 2003 - Dr. Satya Prakash -Studies of human DNA repair  
> diseases in
> yeast
>
> Through the miracle of videotape we now have been able to post most  
> of the
> DNA Repair Interest Group videoconferences from 1998,1999, 2000, 2001,
> 2002 and 2003 on the web site.  These include talks by Drs. Anderson,
> Beernik, Bogenhagen, Bohr, Bradsher, Brash, Brooks, Brosh, Chu,  
> Cleaver,
> Chen, Copeland, Drotschmann, Elledge, Emmert, Essigman, Fornace,
> Friedberg, George, Glazer, Grossman, Hanawalt, Jin, Kashlev, Kraemer,
> Kunkel, Leadon, Liu, Ljungman, Marini, Matson, Matsumoto,  McKay,  
> Mitra,
> Pommier, Ramsden, Rosenquist, Setlow, Schofield, Sharan, Sobol,  
> States,
> Stefanini, Sung, Sutherland, Tainer, Taylor, Tomkinson, Thompson,  
> Vasquez,
> Wang, Wei, Wood, Woodgate, Yanamadala, and Yarosh.
>
> 2. NIH SEMINARS OF NOTE:   June 23 Thu 11:00 AM  Dr. Richard Kolodner
> "Identification of pathways that prevent genome instability".   
> Location:
> Building 50 Room 1227.  For more information contact: Kyungjae (KJ)  
> Myung
> Ph. D. 301-451-8748
>
> 3.    CONFERENCES -  WORKSHOP ON ATAXIA TELANGIECTASIA, ATM AND THE  
> DNA
> DAMAGE RESPONSE JUNE 8-11, 2005, LAKE MAGGIORE, ITALY;   HEALTH,  
> GENES &
> SOCIETY - TEL-AVIV, ISRAEL -JUNE 19-21, 2005; GORDON RESEARCH  
> CONFERENCE
> ON GENETIC TOXICOLOGY - COLBY-SAWYER, NEW LONDON, NH - JULY 31ST- 
> AUGUST
> 5TH 2005;  INTERNATIONAL MEETING ON O6-ALKYLGUANINE-DNA  
> ALKYLTRANSFERASE
> (MGMT). AUGUST 6-9, 2005, KEELE CONFERENCE PARK, UK;  STRUCTURAL  
> BIOLOGY
> OF DNA REPAIR- AUG 28 - SEPT 1, 2005; CELL LINEAGES, GENETIC  
> INSTABILITY
> AND HUMAN DISEASE AUGUST 31-SEPTEMBER 2, 2005, SEATTLE, WA;  9TH
> INTERNATIONAL CONFERENCE ON ENVIRONMENTAL MUTAGENS - SEPT 3-8, 2005  
> - SAN
> FRANCISCO; 11TH CONGRESS OF THE EUROPEAN SOCIETY FOR PHOTOBIOLOGY
> AIX-LES-BAINS, FRANCE, SEPTEMBER 3 - 8, 2005;  RESPONSES TO DNA  
> DAMAGE:
> INSIGHTS FROM CHEMICAL, BIOCHEMICAL, STRUCTURAL BIOLOGY AND CELLULAR
> STUDIES 19-21 SEPTEMBER 2005, BRIGHTON, UK; US-EU WORKSHOP "SYSTEMS  
> LEVEL
> UNDERSTANDING OF DNA DAMAGE RESPONSES" SEPTEMBER 30-OCTOBER 4, 2005,
> STOWE, VERMONT, USA; 5TH INTERNATIONAL 3R SYMPOSIUM NOVEMBER 13-17,  
> 2005,
> - AWAJI YUMEBUTAI INTERNATIONAL CONFERENCE CENTER, AWAJI ISLANDS,  
> HYOGO,
> JAPAN
>
> [Note: A larger and more up-to-date list of conferences can be  
> found on
> the DNA Repair Interest Group web site:
> http://www.nih.gov:80/sigs/dna-rep/ ]
>
>
> 3.1 GORDON RESEARCH CONFERENCE ON GENETIC TOXICOLOGY - COLBY- 
> SAWYER, NEW
> LONDON, NH - JULY 31ST-AUGUST 5TH 2005
>
> Session 1: Keynote talks (Bennett Van Houten/ Samuel Wilson / Peggy  
> Jeggo/
> Marc Vidal)
>
> Session 2: Genotoxicity of endogenous lesions and BER. (Larry  
> Marnett /
> Sankar Mitra/ John Essignman/ Akira Yasui/ Leona Samson)
>
> Session 3: New Developments in excision repair. (Jean-Marc Egly /  
> Caroline
> Kisker/ Kioji Tanaka/ Cilla Cooper)
>
> Session 4: Responses to replication blockage.  (Tom Kunkel/ John  
> Diffley/
> Alan Lehmann/ Jean Wang/ TBA)
>
> Session 5: Double black diamonds of repair:  DNA cross-links and
> protein-DNA cross-links. (Stephen Lloyd/ Peter McHugh/ Laura  
> Neiderhofer/
> Alan D. Andrea)
>
> Session 6: Damage inducible checkpoints and signaling. (Tony Carr/  
> Steve
> Elledge/ Rodney Rothstein/ Yossi Shilo/ TBA)
>
> Session 7: DNA Damage in vivo and somatic mutation in vivo. (Andrew
> Collins/ Bernd Eppe/Vern Walker/  Shinya  Shibutani )
>
> Session 8: Mitochondria: the other site of DNA damage. (William  
> Copeland/
> Susan Ledoux/ Ute Moll/ Takehiko Shibata/ TBA
>
> Session 9: Metals as co-carcinogens. David Wilson/ Andy Kligerman/  
> Anatoly
> Zhitkovich/ Jim Imlay
>
> As in past years this conference seeks to explore mechanisms of
> genotoxicty from molecules to man including systems analysis, and  
> possible
> intervention strategies in disease states. The Keynote Speakers  
> are: Drs.
> Sam Wilson, Penny Jeggo and Marc Vidal. Post-doctoral fellow and  
> students
> are strongly encouraged to participate.
>
> Site for more information: http://www.grc.org/programs/2005/gentox.htm
>
>
> 3.2 INTERNATIONAL MEETING ON O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE  
> (MGMT).
> AUGUST 6-9, 2005, KEELE CONFERENCE PARK, UK
>
> The meeting website is http://www.paterson.man.ac.uk/mgmt/mgmt.jsp
>
> Closing date is June 15th.
>
> For more information contact:
>
>
> Dr Geoff Margison
> Head, Cancer Research-UK Carcinogenesis Group
> Paterson Institute for Cancer Research
> Christie Hospital Trust
> Manchester M20 4BX
> United Kingdom
> Phone:44 (0) 161 446 3183
> Fax: 44(0) 161 446 8306
> E-mail: gmargison at picr.man.ac.uk
>
>
> 3.3 STRUCTURAL BIOLOGY OF DNA REPAIR- AUG 28 - SEPT 1, 2005
> This one day conference will be held during the National ACS.
> For more information contact:
> Caroline Kisker
> Associate ProfessorState University of New York At Stony Brook
> Center for Structural Biology
> Department of Pharmacological Sciences
> Stony Brook , NY 11794-5115
> Tel: (631) 632 1465
> Fax: (631) 632 1555
> E-Mail: kisker at pharm.sunysb.edu
>
> 3.4 CELL LINEAGES, GENETIC INSTABILITY AND HUMAN DISEASE (AN  
> ENVIRONMENTAL
> MUTAGEN SOCIETY SATELLITE MEETING) AUGUST 31-SEPTEMBER 2, 2005,  
> SEATTLE,
> WA
>
> The focus of this meeting is on how the differences in DNA damage,
> mutagenesis, repair and cell death in specific cell types or cell
> lineages influences disease risk or disease pathogenesis.
>
> Organizers: Larry Loeb, Nancy Maizels and Raymond J. Monnat, Jr.
>
> For further information and regsitration, please see:
> http://depts.washington.edu/biowww/ems/
>
>
> 3.5 9TH INTERNATIONAL CONFERENCE ON ENVIRONMENTAL MUTAGENS - SEPT 3-8,
> 2005 - SAN FRANCISCO
>
> This is just a reminder that June 1 is the early-bird deadline for
> discounted registration for the 9th International Conference on
> Environmental Mutagens, to be held in San Francisco this coming  
> September
> 3rd through 8th. You can learn more details and register on-line at
> www.ICEM2005.org. The abstract deadline is also June 1, in order to  
> have
> your abstract included in the published abstract book. However, we  
> will
> accept abstracts after that date and place them in a booklet for
> distribution at the Conference.
>
> The ICEM is held every four years and co-sponsored by the  
> Environmental
> Mutagen Society (EMS) and the International Association of  
> Environmental
> Societies (IAEMS). The first ICEM was held in Asilomar, California  
> in 1973
> and the most recent one in the U.S. was in Cleveland, 16 years ago.
>
> This meeting is particularly important as it combines cutting-edge
> developments in basic science with the application of new knowledge  
> by the
> organizations charged with the testing of potential genotoxins and the
> Governmental agencies that regulate them. There has been increasing
> participation from the DNA repair community in the activities of  
> the EMS
> in recent years, as documented in the program for the upcoming  
> Conference.
>
> The theme of the 9th ICEM, "Global Issues in Genetic Toxicology and
> Environmental Mutagenesis," transcends national boundaries and is  
> timely
> for all peoples of the world. We have learned a great deal about the
> threats to human health from genotoxic chemicals and radiations in our
> environment. We also know of many inherited and acquired genetic
> alterations that predispose to cancer, premature aging, and other
> diseases. The sequencing of the entire human genome and that of  
> many model
> organisms, along with the development of powerful new technologies,
> promise to yield even more impressive advances in the coming  
> decade. It
> should certainly become possible to identify and reduce most of the
> principal environmental hazards that threaten our health and that  
> of the
> planet. These hazards include not only genotoxins but also infectious
> agents and other toxic agents that adversely effect important cellular
> processes.
>
> You won't want to miss the outstanding science and the many  
> opportunities
> for international communication in this field offered by the 9th  
> ICEM. You
> should also check out the pre-conference workshops and the Satellite
> Meetings on specialized topics before and after the main conference.
>
> We look forward to welcoming you to the Hyatt Regency at the  
> Embarcadero,
> in San Francisco, September 3rd through 8th, 2005.
>
> Philip C. Hanawalt
> Chair of the Organizing Committee
>
> Professor of Biology
> Stanford University
> Department of Biological Sciences
> 371 Serra Mall
> Stanford, CA 94305-5020
>
> Tel. (650) 723-2424
> Fax (650) 725 -1848
> Home page: http://www.stanford.edu/~hanawalt
>
> 3.6 11TH CONGRESS OF THE EUROPEAN SOCIETY FOR PHOTOBIOLOGY AIX-LES- 
> BAINS,
> FRANCE, SEPTEMBER 3 - 8, 2005
>
> There will be no ASP meeting this year.  On that occasion there  
> will be a
> symposium devoted to DNA damage and repair. Obviously there will be
> several other symposia dealing with biological consequences of  
> exposure to
> UV and solar radiation (both fundamental and more applied aspects).  
> More
> information is available on the web site of the congress:
> http://www.esp-photobiology.it/2005congress/index.html.
>
>
> 3.7 RESPONSES TO DNA DAMAGE: INSIGHTS FROM CHEMICAL, BIOCHEMICAL,
> STRUCTURAL BIOLOGY AND CELLULAR STUDIES 19-21 SEPTEMBER 2005,  
> BRIGHTON, UK
>
> The call for abstracts and registration are now open for the first  
> meeting
> in the field of DNA Damage from the Chemical Biology Forum and Nucleic
> Acids Group of the RSC in conjunction with the Biochemical Society.
> Deadline for abstracts is 15 Jul 2005.
>
> The aim of the conference is to bring together scientists from several
> disciplines including nucleic acid chemistry, biochemical analysis,
> structural biology and cellular and whole animal studies to help  
> promote
> cross-fertilisation of ideas and collaborative studies between the
> disciplines.
>
> The meeting will cover:
> "       Oxidative DNA Lesions: from Chemistry to Structure to  
> Biochemistry
> to Biology
> "       Mismatch Repair
> "       Double Strand Break Repair and Signalling
> "       Translesion Synthesis and Lesion Bypass
> "       Cross Link Repair/Nucleotide Excision Repair
> Invited speakers include Greg Verdine (Nucleic Acids Award Lecture)
> Harvard University, USA; Steve Jackson, Wellcome/CR-UK Gurdon  
> Institute of
> Cancer & Developmental Biology and Steve West, Cancer Research UK.
>
> Further information can be found on the conference web page:
> http://www.rsc.org/DNA
> Alternatively, please call +44 (0) 1223 432254 or email RSC  
> Conferences at
> conferences at rsc.org
>
> 3.8 US-EU WORKSHOP "SYSTEMS LEVEL UNDERSTANDING OF DNA DAMAGE  
> RESPONSES"
> SEPTEMBER 30-OCTOBER 4, 2005, STOWE, VERMONT, USA
>
> Co-chairs: Anne-Claude Gavin and Marc Vidal
>
> Until now, researchers focused on specific cellular compartments and
> individual pathways to study the DNA-damage response, e.g. cell cycle
> regulation, induction of apoptosis or DNA repair. However, work  
> during the
> past few years has shown that there is strong interplay between  
> each of
> these major cellular defense pathways. Thus, in order to fully  
> understand
> cellular responses to DNA-damage, the cell must be viewed as a large
> network of protein-protein and protein-DNA interactions that  
> responds to
> DNA damage in a systematic way.  Accordingly, it is felt that a  
> systems
> biology approach is needed that studies the genetic, biochemical and
> molecular interactions of the DNA-damage response on a global scale  
> rather
> than as individual pathways of cellular stress response. This will  
> involve
> integration of technologies and scientific disciplines and  
> increasingly
> for joint efforts among complementary fields. The goals of this  
> workshop
> are to analyze the state of the art in the area of DNA-damage response
> analysis, and to stimulate collaboration between researchers in the  
> EU and
> the US in this field. This meeting is a follow-up to the first EU/US
> workshop that was held in Cortona, Italy, Sept 26-30, 2003, and will
> emphasize protein~protein and protein~DNA interactions that  
> underlie this
> global defense network. For more information & registration,  
> please, go
> to:
> http://www.uvm.edu/conferences/systemsbiology05/index.html
>
> Registration deadline is set at July 1, 2005. Registration will be
> accepted on basis of the abstract submitted. Especially for young
> scientists [PhD students and postdocs] sponsored places are  
> available. The
> total size of the meeting will be limited to 110 persons.
>
> 3.9 5TH INTERNATIONAL 3R SYMPOSIUM NOVEMBER 13-17, 2005, - AWAJI  
> YUMEBUTAI
> INTERNATIONAL CONFERENCE CENTER, AWAJI ISLANDS, HYOGO, JAPAN
>
> The mechanism that replicates, maintains, and sometimes alters the DNA
> which contains the genetic information of an organism is the most
> fundamental and important mechanism for life. Three processes (DNA
> Replication, DNA Repair, and Recombination: 3R) that are involved  
> in this
> mechanism are closely related each other. The scope of this  
> Symposium is
> to create a forum for free exchanges of scientific information in a
> relaxed atmosphere and for international collaborations on DNA
> replication, DNA repair and recombination, furthering the analysis  
> of 3R
> mechanisms. This Symposium was established in 1997 and has been  
> held every
> other year until this year (the 5th symposium) in the vicinity of  
> Osaka,
> Japan. We expect about 300 participants. The official language in this
> Symposium is English. We are looking forward to your participation.
> The Symposium web site is: http://www.fbs.osaka-u.ac.jp/ 
> ~int3rsymp2005/
>
> For more information, please contact:
> Kiyoji Tanaka, M.D., Ph. D.
> Human Cell Biology Group
> Laboratories for Organismal Biosystems
> Graduate School of Frontier Biosciences
> Osaka University
> 1-3 Yamadaoka, Suita, Osaka, 565-0871, Japan.
> Tel:+81-6-6879-7971
> Fax:+81-6-6877-9136
> e-mail: ktanaka at fbs.osaka-u.ac.jp
>
>
> 4.      POST DOC AND EMPLOYMENT OPPORTUNITIES: Bethesda, MD;  
> Indianapolis,
> IN; Buffalo, NY; Columbia, S.C.; Worcester, MA; Burlington, VT,  
> Rochester,
> MN; London, UK
> [Note: Check the list for more Job Opportunities on the DNA Repair
> Interest Group web site: http://www.nih.gov:80/sigs/dna-rep/ ]
>
>
> 4.1 NIH POST DOCTORAL FELLOWSHIP - HUMAN DISEASES WITH DEFECTIVE DNA
> REPAIR - BETHESDA, MD
> We are studying molecular, cellular and clinical abnormalities in  
> patients
> with defective DNA repair and possible links of these genes to  
> disease in
> the general population. Current emphasis is on xeroderma pigmentosum,
> Cockayne syndrome and trichothiodystrophy.  A postdoctoral position is
> available for a talented individual (M.D., Ph.D. or MD-PhD) with  
> less than
> 5 years of postdoctoral experience who has knowledge of molecular  
> biology
> and DNA repair.
>
> To apply, send CV and bibliography and names (with contact  
> information) of
> 3 references to:
>
> Kenneth H. Kraemer, M.D.
> Basic Research Laboratory
> National Cancer Institute, NIH
> Building 37 Room 3E24
> Bethesda,  MD 20892
> TEL: 301-496-9033    FAX: 301-496-8419
> e-mail: kraemerk at nih.gov
> http://rex.nci.nih.gov/RESEARCH/basic/lmc/khk.htm
>
> NIH is an equal opportunity employer.
>
>
> 4.2 TWO FULL TIME FACULTY POSITIONS  - PEDIATRIC HEMATOLOGY/ONCOLOGY -
> INDIANAPOLIS, IN
>
> The Department of Pediatrics, Section of Pediatric Hematology/ 
> Oncology at
> Riley Hospital for Children and Indiana University School of  
> Medicine is
> recruiting two full-time academic positions at the
> Assistant/Associate/Full Professor level.  The positions have an  
> emphasis
> on basic and translational research.  This senior position comes  
> with the
> Earl and Betty Herr Endowed Chair in Pediatric Oncology Research.
> Candidates must have strong research background and either current or
> potential for independent funding.  Successful candidates will be  
> expected
> to establish a strong externally funded research program.  Laboratory
> space is in the Herman B Wells Center for Pediatric Research, which  
> has
> ongoing programs in DNA repair, cancer biology, stem cell biology,  
> genetic
> blood disorders, myeloid biology, leukemogenesis and development.  The
> position comes with a generous start-up package, outstanding  
> laboratory
> space and protected time for research-related activities.
>
> The Department of Pediatrics consistently ranks in the top 20  
> nationally
> for NIH funding to pediatric departments.  This recruitment is part  
> of a
> major expansion of the Herman B Wells Center for Pediatric Research, a
> highly interactive and multidisciplinary research center that is  
> part of
> the Department of Pediatrics.  The Wells Center currently occupies  
> 65,000
> sq ft of research space and will continue to expand in the forthcoming
> years. There are currently twenty-six principal investigators, and NIH
> funded areas of research include: developmental pulmonary physiology,
> cardiovascular developmental biology, fetal and neonatal metabolic
> physiology, reproductive and neuro-endocrinology, hematopoiesis,  
> myeloid
> biology and gene regulation, gene therapy, cancer biology and DNA  
> repair.
>
> Indiana University School of Medicine is also home to the nation.s  
> only
> federally sponsored gene vector production and research facility,  
> one of
> three molecular hematology research centers in the country, and a  
> National
> Cancer Institute-designated Cancer Research Center.  In addition,  
> the IUSM
> hosts more than twenty NIH Centers including a Diabetes Research and
> Training Center, an Adolescent Sexually Transmitted Disease Center, an
> Alcohol Research Center, and an Alzheimer.s and Related Diseases  
> Center.
>
> The search committee will begin evaluating applications on April 1,  
> 2005
> and applications will continue to be reviewed until the position is
> filled. Interested applicants should submit a curriculum vitae,  
> summary of
> research accomplishments and future research plans, and the names  
> of at
> least three references to Mark R. Kelly, Ph.D., 1044 West Walnut  
> Street,
> Room 302C, Indianapolis, IN, 46202; email:  mkelley at iupui.edu.
>
>
> 4.3 POSTDOCTORAL POSITION IN PHARMACOLOGY AND CANCER THERAPEUTICS  -
> ROSWELL PARK CANCER INSTITUTE - BUFFALO, NY
>
> Postdoctoral position in pharmacology and cancer therapeutics at  
> Roswell
> Park Cancer Institute is available for studies of cellular  
> responses to
> dna damaging antitumor drugs. The research will examine drug  
> induction of
> pivotal DNA damage response proteins and assess changes in nuclear DNA
> structure as well as chromosomal abnormalities. Emphasis will be on  
> novel
> drug specific DNA damage responses (e.g., ATM independent response to
> enediyne induced DNA double strand breaks JBC 277:20549-20554,  
> 2002) with
> the ultimate goal of uncovering new chemotherapeutic strategies for  
> cancer
> treatment.
>
> Candidates must have a Ph.D. degree or MD and experience in a relevant
> field.
>
> To apply, send a curriculum vitae an description of relevant research
> experience, and contact information for three references to:
>
> Dr. Terry A. Beerman
> Pharmacology and Therapeutics Department
> Carlton and Elm Streets
> Roswell Park Cancer Institute
> Buffalo, NY 14263
> E-mail: terry.beerman at roswellpark.edu
>
>
>
> 4.5 POSTDOCTORAL POSITION IN DNA REPAIR AND RESPONSES TO  
> CHEMOTHERAPY -
> COLUMBIA, SC
>
> A postdoctoral position is available immediately to use molecular
> genetic and pharmacological approaches to study DNA repair, genomic
> stability, and responses to chemotherapy in mammalian cells. The
> NIH-funded project seeks to determine the links between base excision
> repair, recombination and apoptosis in response to chemotherapy that
> inhibits thymidylate synthase. The project is a collaboration with Dr.
> Alan Waldman in the Dept. of Biological Sciences at the University of
> South Carolina. The investigators are also part of the University's
> NIH/NCRR-funded Center for Colon Cancer Research. The center includes
> histology, pathology, statistics, and animal core facilities. We seek
> an enthusiastic and motivated individual holding a Ph.D., with
> experience in molecular biology. Experience in mammalian cell culture,
> DNA and RNA isolation, Southern/ Northern/Western blotting, and RNA
> interference is preferred.
>
> To apply, send a curriculum vitae with bibliography, description
> ofresearch experience, and contact information for three references  
> to:
>
> Michael D. Wyatt, Ph.D.
> Department of Basic Pharmaceutical Sciences
> Coker Life Sciences Building
> University of South Carolina
> 700 Sumter Street
> Columbia, SC 29208
> wyatt at cop.sc.edu
> http://www.pharm.sc.edu/
> http://www.cccr.sc.edu/
>
>
>
> 4.6 POST DOCS  DNA REPAIR ENZYMES, POLYMERASES, AND RECOMBINASES -
> BURLINGTON, VT
>
> The University of Vermont Department of Microbiology and Molecular
> Genetics is seeking Postdoctoral Research Associates with an  
> interest in
> applying a combined genetic, biochemical, bioinformatic and
> crystallographic approach to study DNA repair enzymes, polymerases,  
> and
> recombinases. NIH support is available for individuals with a strong
> quantitative background who aim to strengthen their ability to bring
> multiple disciplines to bear on challenging projects. We provide an
> intense, collaborative environment in which all participants, from
> students to PI's, learn and work together towards understanding these
> central biological processes. Students and postdocs are immersed in  
> the
> theory and practice of all aspects of structural biology, from  
> cloning and
> overexpression to solving and analyzing structures.
>
> The success of our collaborative approach is evidenced by recent
> publications (EMBO J. 2004 23:1483-1493; PNAS 2004  
> 101:10284-10289), and
> by our award of an NIH Program-Project grant to further pursue these
> goals. State-of-the-art research facilities, coupled with established
> investigators eager to share their experience, provide the tools and
> learning opportunities to help young investigators achieve their own
> success.
> The University of Vermont is located in Burlington, Vermont,  
> consistently
> ranked among the best places to live in the US by virtue of its  
> accessible
> world-renowned recreation sites and respect for the environment.
>
> Positions are available immediately in any of our three research  
> groups
> (Sylvie Doubli, structural biology of DNA replication and repair;  
> Scott
> Morrical, homologous recombination and double-strand break repair;  
> Susan
> Wallace, DNA replication and DNA repair).  Interested applications  
> should
> send a CV, a cover letter, and the names of 3 references to:
>
> Debra Stern
> 201 Stafford Hall
> Department of Microbiology and Molecular Genetics
> The University of Vermont
> Burlington VT 05405
> Fax: (802)656-8749
> Email: dstern at uvm.edu
>
> The University of Vermont is an affirmative action/ equal opportunity
> employer.
>
> 4.7 POSTDOCTORAL POSITIONS ARE AVAILABLE TO STUDY DNA DAMAGE  
> PREVENTION
> AND REPAIR MECHANISMS. - UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL,
> WORCESTER, MASSACHUSETTS
>
> Projects include studies of the human and yeast OXR and
> PC4 genes, and their function. (For recent references see: PNAS, 97:
> 14530;
> MCB, 24:3180; and MCB, 24:6084) Requires strong background in
> biochemistry,
> molecular biology, and genetics. Send C. V. and names, phone  
> numbers, and
> e-mail addresses of at least three references to: Michael Volkert,  
> Ph.D.,
> Dept. Molecular Genetics and Microbiology, University of Massachusetts
> Medical School, Worcester, MA 01655, or by E-mail to:
> Michael.Volkert at umassmed.edu.
>
> Sincerely
>
>
> Michael Volkert, Ph.D.
> Professor
> --------------------
> Department of Molecular Genetics and Microbiology
> University of Massachusetts Medical School
> Worcester, Massachusetts 01655
> --------------------
> Phone: (508) 856-2314
> Fax: (508) 856-5920
> Email: Michael.Volkert at umassmed.edu
>
>
> 4.8 POST DOCTORAL FELLOWS - DNA EXPANSION IN HUMAN DISEASE -  
> ROCHESTER, MN
>
> Funding for 2 postdoctoral fellows at the Mayo Clinic in the area  
> of DNA
> expansion and its role in human disease. Areas of interest:
> * Genetic Mechanisms of trinucleotide expansion mutations in animals
> * Biochemistry of DNA Repair enzymes and their defects in disease
> * DNA Repair
> * DNA breakage in neurons.
> * Repair and cell death mechanisms in neurodegeneration and cancer.
>
> Experimental systems are varied and include mice, cells, purified
> proteins, microscopy/ imaging. Therefore, qualified individuals with
> expertise in one of many fields are welcome to apply. Salary is
> commensurate with experience. I will be available at the upcoming ASM
> Repair Meeting in Bermuda.
>
> The Mayo Clinic offers a world-class research environment including:
> * Excellent salaries and benefits.
> * Strong Basic and Clinical research
> * Access to human and clinical materials
> * Core or collaborative service labs in transgenic mice, DNA and  
> protein
> synthesis, protein analysis, NMR, mass spectrometry, stem cell,
> production, epidemiology and statistics, monoclonal antibody  
> production,
> general clinical research, electron and confocal microscopy, stem cell
> laboratory, Immunological Core lab, biomedical imaging and computers,
> section of engineering.
>
> Cynthia T. McMurray, Ph.D.
> Professor and Distinguished Mayo Investigator
> Departments of Molecular Pharmacology and Experimental  
> Therapeutics, and
> Biochemistry and Molecular Biology
> Mayo Clinic Rochester
> 200 First St. SW, Guggenheim 7
> Rochester, MN 55905
> e-mail: mcmurray.cynthia at mayo.edu
> (507) 284-1597 Direct Phone
> (507) 284-9111 Fax
> (507) 284-2696 Timothy Farnham, Assistant to Dr. McMurray
>
>
>
>
>
>
>
>
> 5.0  COMMERCIAL REAGENT SOURCES
> [Note: There are more commercial reagent sources listed on the DNA  
> Repair
> interest group website: http://www.nih.gov:80/sigs/dna-rep/    These
> sources are listed as a convenience to our readers and do not  
> constitute
> an endorsement of any of these companies or their products.]
>
> 5.1 MBL International offers many kits and reagents for research on  
> DNA
> Damage
> and Repair. MBL is especially excited to introduce two unique  
> monoclonal
> antibodies that can detect the major classes of UV-induced  
> photolesions:
> Cyclobutane Pyrimidine Dimers (CPD) or pyrimidine-[6-4]-pyrimidinone
> photoproducts (6-4 PP). These antibodies were established by Dr. T.  
> Mori
> et
> al. in Japan.
>
> For more information on these antibodies, please visit the  
> following links
> http://www.mblintl.com/mbli/catalog/pdf/d195-1.pdf (anti-6-4PP)
> http://www.mblintl.com/mbli/catalog/pdf/d194-1.pdf (anti-CPD)
> or contact
>
> Suzan Oberle, Ph.D.
> Product Manager/Technical Service Manager
> MBL International
> 800-200-5459
> suzan at mblintl.com
> www.mblintl.com
>
>
> 5.2 Biocompare - This website www.biocompare.com calls itself .The  
> Buyer.s
> Guide for Life Scientists. This site includes comparisons of many  
> reagents
> that are useful for DNA repair studies including a listing of  
> antibodies.
>
> 5.3 Genetex - Antibodies for DNA repair www.genetex.com Located in  
> Texas.
>
> 5.4 Phoenix BioTechnologies Inc. - cis-syn thymine dimers now  
> available at
> 0.2 and 1 umol scale synthesis. As a top provider of specialty DNA,  
> RNA
> and LNA synthesis services to labs with unique requirements, Phoenix
> BioTechnologies also announces synthesis services for oligonucleotides
> containing thymine glycol. Working with Glen Research, we have  
> optimized
> synthesis with these amidites to attain excellent coupling  
> efficiencies
> and high product yields.
>
> For additional information, please contact us at your convenience  
> through
> the information listed below.
>
> Donna Brown
> Company Scientist
> Phoenix BioTechnologies, Inc.
> 1000 Meridian Street
> Huntsville, AL 35801
> Toll-free 866-319-0900
> FAX 256-319-0902
> dbrown at phxbio.com  http://www.phxbio.com
>
>
> 5.5 Abcam Ltd ( www.abcam.com ) - At present, we have a fairly  
> substantial
> range of products including those relating to DNA damage and repair  
> (246
> in total), and are actively developing this as we speak.
>
> Please find a hyperlink provided below for your review.
>
> http://www.abcam.com/index.html? 
> pageconfig=catalog_byclass&intClassID=6
>
> Thank you in advance for your time and kind consideration.
> Miss Lesa Rodgers
> Marketing Assistant
> Abcam Ltd
> 21 Cambridge Science Park
> Milton Road, Cambridge,
> Cambridgeshire CB4 0TP
> United Kingdom
> www.abcam.com
>
>
> 5.6 Bethyl Laboratories, Inc. - Antibodies for DNA Damage/Repair and
> related research (www.bethyl.com)  New antibodies include SDS3, DMAP1,
> KIF14, DIS, MCM2, MCM3, MCM4, MCM6, MCM7, MCM10, Claspin, BRD2,  
> Pumilio 1,
> Pescadillo, Mre11, NBS1, SERCA2, AMPK and RFC1. http://www.bethyl.com
>
> 5.7  Reliable Biopharmaceutical Corporation - As the leading U.S.
> manufacturer of modified nucleic acids, we wanted to introduce you  
> to our
> newest product: cis-syn TpT Cyclobutane Dimer Phosporamidite.  
> Specially
> developed for the DNA repair and research markets. You can see our
> homepage and our TpT Dimer Amidite webpage to better understand our
> company and products.
>
> If I or my staff can answer any of your specific questions, please  
> call at
> your convenience.
>
> Sincerely,
> Sourena Nadji, Ph.D.
> Reliable Biopharmaceutical Corporation
> Director of Research and Development
> (314)429-7700
> http://www.reliablebiopharm.com/
>
> 5.8 Novus Biologicals, Inc, Littleton, CO - Antibodies for DNA Repair
> Research (http://www.novus-biologicals.com/research.php/8) and other
> research applications (www.novusbio.com). New antibodies include  
> RNase L,
> ATRIP, CTR1, BRCA1, 14-3-3 gamma, DHX15, phospho-CREB [Ser121],  
> FANCD2,
> BRIP
> 1, carbonic anhydrase IX, and p73.
> For more information contact:
> Novus Biologicals, Inc.
> 303-730-1950  novus at novusbio.com
>
> 5.9 Santa Cruz Biotechnology, Inc, Santa Cruz, CA - Antibodies for
> research applications.  Please find specific product information at
> http://www.scbt.com
>
> 5.10 Austral Biologicals, Inc, San Ramon, CA. - Antibodies for  
> research
> applications.
> Please visit our web site: http://www.australbio.com
>
> 5.11 Cascade Bioscience - Antibodies to various FANC proteins.   
> Here is a
> link to a website we have in development featuring FANC antibodies.
> http://www.cascadebioscience.com/test/
> Patrick Foley, President, Cascade Bioscience, Inc, 37 Pierrepont Rd,
> Winchester, MA 01890, Phone 781-721-4758 Fax 781-729-4731
>
> 5.12 Rockland - the leader in antibody based products is located near
> Philadelphia, PA. Primary antibodies include Apolipoproteins,  
> Collagens,
> Cytokines and Transcription Factors. Secondary antibodies are  
> conjugated
> to a broad range of enzymes and fluorphors. ROCKLAND has developed new
> antibodies to study Signaling Pathways. We produce our own  
> antibodies. It
> is for this reason researchers choose us for their custom antibody  
> needs.
> Primary Antibodies
> AKT Signaling Antibodies; Phospho and Pan reactive antibodies  
> involved in
> the PI-3 kinase pathway
> DNA Damage and Repair AntibodiesPhospho ATM antibodies, mTOR  
> antibodies
> and many more
> Cancer Research Antibodies; Antibodies directed against Cell Cycle
> proteins, Chromatin and Apoptosis targets
> Neuroscience Antibodies; Beta Amyloid, Dab1, Superoxide Dismutase
> antibodies are just a few
> Ubiquitin & UBL; High quality antibodies like SUMO, ISG15 and  
> Ubiquitin
> Epitope Tag Antibodies; 6X HIS, HA, GST, Myc, RFP, Biotin, GFP and  
> their
> conjugates
> Special (United States and Canada only)
>
> Our product listing [ http://www.rockland-inc.com ] currently contains
> thousands of antibodies. You may also search for your favorite  
> antibody in
> our ever growing database. To complete your experiment, we also have a
> number of other products and services that may interest you, to  
> visit our
> web site click here. To obtain a Rockland catalog, please click here.
> Are you looking for an antibody that you just cant find? Get a  
> quote for
> Custom Antibody Production.
> Custom Monoclonal Antibody Production
> Custom Polyclonal Antibody Production
> Regards,
> Tabitha A. Bauman
> Rockland Immunochemicals, Inc.
> 650 Englesville Road
> Boyertown, PA 19512
>
>
> 6       ELECTRONIC CONTACTS:
> 6.1     Check out the DNA Repair Interest Group web site:
> http://www.nih.gov:80/sigs/dna-rep/
> You can find the schedule for future DNA Repair Interest Group
> videoconferences and a listing of past videoconferences (with links  
> to the
> videoarchive) as well as a current list of JOB OPPORTUNITIES in DNA  
> repair
> and MEETING NOTICES.
>
> 6.2     Encourage your colleagues who are interested in DNA Repair to
> request that they be added to this DNA Repair Interest Group listserve
> e-mail list by sending a request by e-mail to: listserv at list.nih.gov
> Leave the subject  blank. In the message field, type in: subscribe
> DNARepair-L your name
>
>        Alternatively, by filling out the form on the website
> (http://www.nih.gov:80/sigs/dna-rep/ ) you can both add your name  
> to the
> e-mail list and have your name posted on the website.  If you want  
> your
> name to be listed you can fill out the .Join the SIG. form on the  
> web site
> and add your name to the listing of members.  If you are not at NIH  
> then
> be sure to click the .other. box and then fill in the name of your
> institution.
>
> 6.3     Archives of these listserve mailings can be found at
>        http://list.nih.gov/archives/dnarepair-l.html  or via links  
> from
> the DNA Repair Interest Group web site:
> http://www.nih.gov:80/sigs/dna-rep/
>
> 6.4     I will be happy to relay information about post-doctoral
> positions, jobs and meetings and other information related to DNA  
> Repair.
> Please send me an e-mail message (kraemerk at nih.gov) and I will  
> incorporate
> it into the next announcement list and post it on the DNA Repair  
> Interest
> Group web site: http://www.nih.gov:80/sigs/dna-rep/ .
> (This list goes to nearly 1300 scientists around the world who are
> interested in DNA repair.)
>
> Kenneth H. Kraemer, M.D.
> Chief, DNA Repair Section
> Basic Research Laboratory
> National Cancer Institute
> Building 37 Room 3E24
> Bethesda,  MD 20892
> 301-496-9033    FAX: 301-496-8419
> e-mail: kraemerk at nih.gov
> DNA Repair Interest Group web site:
> http://www.nih.gov:80/sigs/dna-rep/
>
>

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