Inhibition of DSI Kinase by Influenza

HPUTZ at BIOTECHNET.COM HPUTZ at BIOTECHNET.COM
Tue Jun 22 10:17:21 EST 1993



I'm a newcomer to this bulletin board and since I have yet to hear
from any of you, I thought that I would try to get the ball rolling.

It is common knowledge amongst virologists that influenza, along with
many other viruses , is capable of blocking the shut down of host
cell protewin synthesis by inhibiting the interferon induced DSI
kinase pathway.  I was wondering if there n is any new data and/or
ideas as to how this mechanism works?

Henry Putz
Dept. of Virology and Oncopharmacology
Sterling Winthrop Pharmaceuticals



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