Retrovirus question

n.panjwani at ic.ac.uk n.panjwani at ic.ac.uk
Fri Dec 2 05:36:39 EST 1994


I have two questions about HIV that arose in a discussion I had today, and
we reached no satisfactory conclusion. Perhaps one of you is
pre-enlightened:

[1] When HIV RNA is reverse transcribed, why is the polyA tail not
    transcribed to polyT?

[2] How many copies of provirus can exist in a cell, i.e. how many HIV cDNAs
    can integrate? Does multiplicity have any known effect on pathogenesis?

Thank you for your time,

Naveed Panjwani
Dept of Clinical Sciences
London School of Hygiene and Tropical Medicine
University of London, UK.

E-mail:  n.panjwani at ic.ac.uk




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