A little question about an idea

RYBICKI, ED ED at molbiol.uct.ac.za
Tue Oct 11 06:25:27 EST 1994


> I write a little science fiction and I like to keep my ideas close
> enough to real science so that someone who actually knows about 
the
> field (physics, biology, whatever) would have to think for a few
> moments to find any flaws.  

Bravo!

> Idea for fighting retroviruses:
> 
> Manufacture a little retrovirus.  ...
> Inject a person and these little viruses inject their code into 
cells
> around the body, but only in cells actively infected by 
retroviruses
> does the code become active.  In those cells surface protein flags 
are
> manufactured and the immune system easily finds the actively 
infected
> cells.

intriguing, and could potentially work - IF RT works on extraneous 
RNA, and not only on RNA it is co-injected with?

> Alternatively, the "safe" retrovirus has code that causes a cell 
to
> lyse (do I have the word right... dissolve/explode?).

Above would only do what HIV/lytic retroviruses do, and make the 
situation worse - what do others think?

  _________________________________________________________________
 | Ed Rybicki, PhD          |         Well, I tip my hat           |
 | (ed at micro.uct.ac.za)     |      To the new constitution         |
 | Dept Microbiology        | Take a bow for the new revolution... |
 | University of Cape Town  |  Then I get on my knees and pray     |
 | Private Bag, Rondebosch  |   We don't get get fooled again...   |
 | 7700, South Africa       |                                      |
 | fax: xx27-21-650 4023    |      - Pete Townshend, 1972          |
 | tel: xx27-21-650 3265    |      (Won't get fooled again)        |
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