vaccination against zoster

DANDERSON at PRL.PULMONARY.UBC.CA DANDERSON at PRL.PULMONARY.UBC.CA
Tue Apr 11 09:21:07 EST 1995


>Subject: vaccination against zoster

It would be unlikely that this would work very well. Elderly patients who are 
prone to Zoster usually have quite adequate levels of antibodies against 
Zoster, from previous exposure to Varicella. IF you were to immunize them with 
live varicella vaccine (just becoming available in the US but available in 
Japan for years), you might predict that the vaccine wouldn't "take" due to 
pre-existing neutralizing antibodies. Another problem is that Zoster is quite 
sporadic and a trial would take years of surveillance and thousands of 
vilunteers, just to wait for the occasional occurrence of Zoster.




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