HHV-6: The T-Cell Killer

James Scutero jscutero at panix.com
Tue May 16 16:52:20 EST 1995

In article <Pine.SOL.3.91.950515220402.16814A-100000 at corona> Patrick O'Neil <patrick at corona> writes:
>On 15 May 1995, James Scutero wrote:
>> NEW YORK NATIVE/May 22, 1995
>> HHV-6 May Not Even Need HIV to Destroy The Cells That Prevent 
>> Opportunistic Infections
>> by Neenyah Ostrom
>>      What sets off the cascade of events that results in the 
>> destruction of the immune systems of "AIDS" patients? Although the 
>> putative causal agent of the syndrome, HIV, is believed to orchestrate 
>> the immune system's collapse, no one has been able to explain how it 
>> does it. Meanwhile, another virus, Human Herpes Virus 6 (HHV-6), has 
>> been found to kill immune system cells directly-including T-cells, the 
>> loss of which is the agreed-upon hallmark of the syndrome-without any 
>> mystery or putative indirect mechanisms that have been attributed to 
>> HIV. Now, new research from Robert Gallo's National Cancer Institute of 
>> Tumor Cell Biology reveals that HHV-6 infection is required for HIV to 
>> be able to infect some T-cells.
>Interesting...but I find it rather difficult to believe that an EXTREMELY 
>common virus such as HHV-6 would be THE cause of AIDS.  Certainly, it 
>cannot be ruled out as A factor but it cannot be THE factor.  HHV-6 is 
>the cause of a very common childhood disease, roseola, which itself has 
>been known since before 1910, yet there was no AIDS back then.  The fact 
>that roseola (exanthem subitum) has been know since at least 1910 implies 
>that HHV-6 has been common for many decades if not longer.  How can such 
>a widespread and common virus only now cause AIDS?  Some new supermutant 
>variant?  No evidence for that at all.  
Exanthem subitum is caused by variant B. This article is about variant A.

Please follow-up this discussion to misc.health.aids.
-James M. Scutero, original proponent of misc.health.aids
 misc.health.aids WWW homepage: http://www.panix.com/~jscutero

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