Hepatitis C virus antibody specificities?
akirby at eastman.ucl.ac.uk
Mon Jun 3 06:00:37 EST 1996
Biogenesis market several different monoclonals directed against HCV
core protein amino acid sequence 1-120. These are clones 215/057 and
0126. A recent paper by Gonzalez-Peralta, Fang.....and Lau (J Hepatol
1994; 20: 143-147) said that best immunohistochemical results were
obtained using mAbs directed against core protein aa26-45.
So, does anybody know precisely which sequence Biogenesis mAbs are
against, as they have been unable to help, or can someone recommend a
mAb known to be suitable for immunochemistry?
Finally, if all else fails, does anybody know any of the authors of
the HCV mAb paper mentioned. They are based at the University of
Florida, Gainsville, USA.
Alun Kirby and Giovanni Lodi
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