RNA pol II fidelity

Karl Fischer tyr-2 at bones.biochem.ualberta.ca
Thu Mar 14 01:00:20 EST 1996


Since retroviruses and pararetroviruses replicate via an RNA intermediate,
the mutation frequency in the final ds DNA form is a consequence of the
fidelity of both host RNA pol II and the viral RT. However, the only
information regarding RNA pol II fidelity was from Eur. J. Biochem. a
couple of years ago and this was for enzyme isolated from wheat germ.

Anyone know if fidelity of mammalian RNA pol II has been examined recently
(journal, meeting proceedings/abstract)?

Cheers

Karl the hepB guy

-- 
Karl Fischer
tyr-2 at bones.biochem.ualberta.ca





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