HIV protease

maxime.lecerf maxime.lecerf at wanadoo.fr
Mon Aug 13 04:08:18 EST 2001


Hello everyone.

I would like to know what is the role played by the HIV protease, I mean the
one which is inhibited by antiprotease drugs (sucha as Nelfinavir /
Viarcept).
Is it this enzyme which cuts the large polypeptide coded by the
monocistronic HIV genome in order to build the capside ?
Could you tell me what kind of molecule is the inhibitor, what is its
specificity, and how does it work ?

Thank you.
maxime.lecerf at orange.fr



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