[Virology] Re: Adenovirus info. request (2)

vaxguy khaffer at gmail.com
Tue Aug 22 14:11:43 EST 2006


Shelly,

The infectivity potential of the virus can decrease with a freeze thaw
or other inactivating steps. The actual virus particle count probably
does not change. To avoid titer losses: aliquot samples, include a
stabilizer or freeze samples.
Regards,

Keith

Shelly Ogiste wrote:
> Hi I was hoping you could help me with a question. How can you "lose
> titer" in a freeze thaw cycle? If I take a liquid and repeatedly freeze
> it and thaw it, how is the concentration going to change?
> 
>  
> 
>  
> 
> Shelly



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