NATO ADVANCED STUDY INSTITUTE

TAYLAN CONSULT1 at TRMETU.BITNET
Fri Dec 4 01:55:28 EST 1992


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                                              Preliminary  Announcement


                     NATO ADVANCED STUDY INSTITUTE
                     -----------------------------

          MOLECULAR ASPECTS OF OXIDATIVE DRUG METABOLIZING
      ENZYMES AND THEIR SIGNIFICANCE IN ENVIRONMENTAL TOXICOLOGY,
                 CHEMICAL CARCINOGENESIS,AND HEALTH

                      JUNE 20 -- JULY 2 , 1993
                          KUSADASI-TURKEY


ORGANIZED BY:   Emel ARINC (TURKEY), Wolfgang KLINGER (GERMANY),
                 John B. SCHENKMAN (USA), John J. STEGEMAN(USA)



    The primary aim of Institute will be on the recent advances in
  biochemical, regulatory and molecular aspects of oxidative drug
  metabolizing enzymes. Mainly cytochrome P450 dependent and Flavin
  containing monooxygenases will be covered. Significance of these
  enzymes in genotoxicology, environmental toxicology, chemical car-
  cinogenesis will be discussed. Therapeutic P450 inhibitors and
  cytochrome P4501A1 induction in fish and its potential use in bio-
  chemical monitoring will be considered as special topics of interest.



   LECTURERS:

   Richard F. ADDISON (CANADA)       Wolfgang KLINGER (GERMANY)
   Diana ANDERSON (UK)               Sergei V. KOTELEVTSEV (RUSSIA)
   Emel ARINC (TURKEY)               David KUPFER (USA)
   Johannes DOEHMER (GERMANY)        Anthony Y.H. LU (USA)
   Yoshiaki FUJII-KURIYAMA (JAPAN)   Franz OESCH (GERMANY)
   Anders GOKSOYR (NORWAY)           Richard M. PHILPOT (USA)
   John W. GORROD (UK)               John B. SCHENKMAN (USA)
   Helmut GREIM (GERMANY)            John J. STEGEMAN (USA)
   Ernest HODGSON (USA)              Hugo Vanden BOSSCHE (BELGIUM)
   Eric F. JOHNSON (USA)             Chung S. YANG (USA)


                         SESSIONS

  Session I   : BIOCHEMISTRY AND MOLECULAR BIOLOGY OF THE MICROSOMAL
               CYTOCHROME P450 ISOZYMES
  Session II  : FLAVIN CONTAINING MONOOXYGENASES
  Session III : METABOLISM AND TOXICITY OF DRUGS AND OTHER XENOBIOTICS
  Session IV  : GENOTOXICOLOGY, PREDICTIVE TESTS, CHEMICAL
               CARCINOGENESIS AND CYTOTOXICITY
  Session V   : THERAPEUTIC AGENTS AND CYTOCHROME P450
  Session VI  : ECOTOXICOLOGICAL  ASPECTS OF CYTOCHROME P450 AND
               BIOCHEMICAL MONITORING OF AQUATIC POLLUTANTS



    Lectures, poster sessions, oral presentations and discussions
will be held from 9:00 h. to 12.30 h. and from 16.30 h. till 19:00 h.
    Approximately 75 participants will be admitted. The Institute is
located in a five-star KORUMAR Hotel which has its own beach and Con-
ference rooms in KUSADASI, on the Aegean Coast.


  DEADLINE FOR APPLICATION:     February 20, 1993

  FINANCES:
     Participants are expected to cover their own travel and living
 expenses. A limited number of grants covering (part of) these expenses
 will be available for participants from NATO countries. No registration
 fee is due. Upon acceptance, a non-refundable deposit of 100 US dollars
 will be asked.


 For application forms, write to

 Dr. Emel ARINC
 Director of ASI
 Middle East Technical University
 ODTU
            TR 06531 ANKARA-TURKEY


 Fax: (90) (4) 210 12 79
 Telex no: 42761 ODTK TR
 Tel: (90) (4) 210 10 00 ---> Ext. 3105

 For information through E-mail contact Muzaffer TAYLAN
 CONSULT1 at TRMETU.BITNET



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