refining part of a structure

Bob Grant grant at
Wed Jun 18 09:49:59 EST 1997

I have been warned by a colleague that it is inadvisable to refine just
a small part of a model in XPLOR while keeping most of the atoms fixed. 
Is this really true?  If so, why?

Robert Grant, Ph.D.
Department of Biological Chemistry and Molecular Pharmacology
Harvard Medical School
Boston, MA
email: grant at

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