mike colaneri mike at SPIN.AECOM.YU.EDU
Thu Sep 25 15:33:08 EST 1997

	A native diffracts to 2.0 A and has been refined.  An inhibitor
complex is isomorphous to the native and diffracts to 3.0 A.  Is it 
meaningful to refine the native coordinates against a lower resolution 
data set except for rigid body refinement and the residues in the active
site or those residues that actually change?  Any suggestions
would be greatly appreciated.
					Michael Colaneri			

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