cara at HELEN.UCSF.EDU
Thu Jul 16 21:22:19 EST 1998
Postdoctoral Position Available to study the role of epidermal growth factor
receptor (EGFR/ErbB2/HER2) family in transformed phenotype.
These members of PTKR superfamily are particularly interesting
since they are not homologous to any known structure and they
have been implicated more than any other in the
development of human cancers. We have 3.0A data from native crystals.
Recombinant expression systems which produce adequate amounts of protein
for structure determination have been established in the lab.
These structural studies are complemented by functional analysis
using molecular and cellular biology techniques including display
As a member of the laboratory, the post doctoral fellow would
interact with the large&fun structural community at U.C.S.F.
The crystallography facility is equipped with 3 state of the art
detector systems. Also, we are within 30 minutes of SSRL and ALS. SSRL has
3 protein crystallography beamlines and 2 are suitable for MAD phasing.
The successful candidate will participate in all aspects of
structure determination and will have a background in
structural biology and an interest in drug design.
This position is available for up to 3 years i.e. super project & S.F.,Calif.
Candidates should fax or email their resume and a brief description of their
>1001 Potrero Ave.
>San Francisco, Calif. 94110
>cara at helen.ucsf.edu
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