modified nucleotides parameter files

[Yoram Puius]

Jason Holland wrote:
> 
> Hello,
> 
> I am curious about generating X-PLOR topolgy and parameter files for
> modified RNA nucleotides, such as pseudouridine and T6A.  What programs
> or files in X-PLOR do I need to run or modify to accomplish this.
> 
> Thanks,
> 
> Jason Holland

For all of your heteroatom needs, first check out 
http://alpha2.bmc.uu.se/hicup/

and if you still need to design the parameter/topology files yourself,
try Gerard's XDICT service
http://alpha2.bmc.uu.se/hicup/xdict.html

or his XPLO2D program (linked from the page above).

HTH,
	Y



-- 
_______________________________________________________________________
Yoram A. Puius                Albert Einstein College of Medicine
M.D.-Ph.D. Student            Department of Biochemistry
mailto:puius at aecom.yu.edu     1300 Morris Park Avenue, Bronx, NY  10461
        http://www.geocities.com/Athens/Forum/7504
_______________________________________________________________________
I'm not afraid of succeeding nor am I of trying -- but
to say I knew exactly what I'm doing would be lying.     - Meryn Cadell