Iodination of Tyr!?

dirk bussiere dirk at whitesws.mc.duke.edu
Thu Mar 17 22:17:16 EST 1994


My protein has 12 tyr's in it, and I would desperately like to
iodinate one or more of them and use this as a derivative.  I am
using Sigler's method of generating I3-.  Does anyone have any other
references on how tyrosine iodination can be accomplished.  My lab has
had varying success with Sigler's method (One success, three failures),
and I would be willing to entertain any other suggestions.





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