protein-protein docking program?

C.S.RAMAN raman at BIOC01.UTHSCSA.EDU
Fri Apr 21 10:49:28 EST 1995


Yu:

> I am studying the interaction of a protein enzyme with a protein substrate.
> >From mutation studies, I know roughly which region of the enzyme interacts
> with which region of the substrate.  Can someone recommend a program to 
> predict the docking of these 2 proteins?  It would be best if the results 
> can be visualized graphically.  Thanks
I higly recommend the program DOCK (v3.5) for what you want to do. This
program is very powerful for doing both enzyme-substrate and
protein-protein interaction modelling.

For an academic license for DOCK 3.5 contact:

Paul J. McCloskey
Project Administrator
UCSF-Molecular Design Institute
513 Parnassus Ave., U64B
San Francisco, CA  94143-0446
(tel) 415.476.9031      (fax) 415.476.9124

Additional information on the latest version of DOCK can be found on
Tack Kuntz's web server:

http://www.cmpharm.ucsf.edu/kuntz/kuntz.html

Cheers
-raman
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   _/                           C.S.RAMAN                                  _/
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