kao_c at REO.MED.UPENN.EDU
Fri Feb 3 00:47:03 EST 1995
I am thinking about connecting two DNA fragments to make a fusion protein.
Because these two DNA fragments are not in frame, I want to add some interval
DNA sequences between them. I also try to prevent these interval amino acids
from interving these two proteins' structures so that I can preserve their
individual functions. What will be the best choice for such interval amino
acids? I am thinking about Gly, Ala, Val, Leu, and Ile. Are they suitable
for this purpose? Where can I find some guide for such design? Any suggestion?
Thanks in advance!
CCK at PA, USA
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