(none)

Chih-Ching Kao kao_c at REO.MED.UPENN.EDU
Fri Feb 3 00:47:03 EST 1995


Hello!
  I am thinking	about connecting two DNA fragments to make a fusion protein.
  Because these	two DNA	fragments are not in frame, I want to add some interval
  DNA sequences	between	them. I	also try to prevent these interval amino acids
  from interving these two proteins' structures so that I can preserve their
  individual functions.	What will be the best choice for such interval amino
  acids? I am thinking about Gly, Ala, Val, Leu, and Ile. Are they suitable
  for this purpose? Where can I	find some guide	for such design? Any suggestion?
  Thanks in advance!

      CCK at PA, USA







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