Structural basis for protein thermostability

Ronald Knegtel knegtel at
Tue Jun 27 04:54:14 EST 1995

Dear Netters,

I'm working on a thermostable enzyme and I'm looking for references
to review articles/papers/books dealing with the structural and/or
physico-chemical basis for protein thermostability. I understand that
the problem is not yet well understood and that several factors are
thought to be important (disulphide bridges, hydrophobic effects etc.)
but I would like to have some recent overview of the current ideas 
in this field. Any help is appreciated, either through E-mail or in 
this group.


Ronald Knegtel
knegtel at

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