crystallization at low ionic strength

Bob Cudney xtalrox at
Wed Dec 4 21:54:13 EST 1996

2. Could anyone suggest or describe methods they have found useful in
screening for crystallization conditions at low ionic strength?

Try the following reference:

Harris et al "Crystallization of intact monoclonal antibodies", 
Proteins: Structure, Function, and Genetics, 23:285-289 (1995)

Here a low ionic strength screen using PEG is described.

Bob Cudney - Hampton Research (xtalrox at

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