>Dear Modelers,
>>We have a protein for which the crystal structure has not been
>determined. Another protein from a family of which our protein is a
>member has had its crystal structure determined.
>>Does anyone know of a program that I could use to make a prediction of
>the tertiary structure of our protein based on the comparison of the
>secondary structures of the two proteins mentioned above?
>>Thanks in advance,
>>Joe Callos
>Penn State U
>jdc6 at email.psu.edu
There are several programs, to name a few:
a. use swiss-model service
http://expasy.hcuge.ch/swissmod/PROMODSERV.html
b. you can buy the program xlook, which uses segmod (Michael Levitt), to
build a structure based on homology.
http://www.msc.com/msc.html
c. Chris Sander
Chris.Sander at EBI.AC.UK
has a program which built a structure based on homology
and many others
Miri