IUBio

secondary to tertiary

Miri Hirshberg m-hirshb at anika.nimr.mrc.ac.uk
Wed May 22 02:28:02 EST 1996


>Dear Modelers,
>
>We have a protein for which the crystal structure has not been
>determined. Another protein from a family of which our protein is a
>member has had its crystal structure determined.
>
>Does anyone know of a program that I could use to make a prediction of
>the tertiary structure of our protein based on the comparison of the
>secondary structures of the two proteins mentioned above?
>
>Thanks in advance,
>
>Joe Callos
>Penn State U
>jdc6 at email.psu.edu

There are several programs, to name a few:

a. use swiss-model service 
 
   http://expasy.hcuge.ch/swissmod/PROMODSERV.html

b. you can buy the program xlook, which uses segmod (Michael Levitt), to
   build a structure based on homology.

   http://www.msc.com/msc.html

c. Chris Sander

   Chris.Sander at EBI.AC.UK

   has a program which built a structure based on homology

and many others

Miri





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