choosing amino acids for site specific mutations

[Mark A. Saper]

Hi Mariylyn,

Since you are really shooting in the dark here, why don't you just do Ala
substitutions?  The problem is, how are you going to assay any changes?  

Mark
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Dr. Mark A. Saper                                saper at umich.edu
Biophysics Research Division                 Phone: (313) 764-3353
The University of Michigan                     FAX: (313) 764-3323
930 N. University Ave., Ann Arbor, MI 48109-1055