Post-doc position available / FHCRC / Seattle

Roland K. Strong rstrong at fred.fhcrc.org
Thu Aug 21 08:55:31 EST 1997


I have an opening for a post-doc, available immediately, to participate
in the
crystallographic analysis of proteins involved in mucosal immune
responses. 
Candidates should be experienced macromolecular crystallographers.  The
most
immediate project is the determination of the crystal structure of the
class I
MHC homologue MICA.  We have grown diffraction-quality crystals with
recombinant protein expressed in my laboratory.  Unlike class I MHC
proteins,
MICA does not present peptide antigens, does not associate with b2-
microglobulin, and is almost exclusively expressed on gut epithelium
regulated
by promoter heat shock elements.  One allele of MICA is associated with
the
multisystem, inflammatory condition Behçet’s syndrome.  The project is
to
complete the crystallographic analysis of MICA and to eventually examine
the
interaction between MICA and its ligands.  There are four Structural
Biology
groups at the Fred Hutchinson Cancer Research Center contributing to an
extremely interactive environment with state of the art data collection
and
computing facilities.  The Seattle area is dynamic and cosmopolitan, and
offers a rich variety of outdoor activities.

FHCRC is an equal opportunity employer committed to work force
diversity.

When applying, please provide a C. V. and at least two references.

Roland K. Strong

Division of Basic Sciences
Fred Hutchinson Cancer Research Center
1100 Fairview Avenue North - Mailstop A3-023
P.O. Box 19024
Seattle, Washington 98109-1024

(206) 667-5587
(206) 667-7730 fax




More information about the Xtal-log mailing list