structs vs reality?

John Kuszewski johnk at spork.niddk.nih.gov
Tue Feb 25 15:37:46 EST 1997


Hi,

I'm writing my thesis now, so I'm starting to 
ponder the big questions.  Here's my current one:

How well do xray or NMR structures actually model
reality in vivo?  

I've seen some old papers showing that some enzymes
still work in the crystalline state, but there 
must be something else about this.

Can anyone point me toward some references?  

Thanks!

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John Kuszewski                     ||  |/  /|  ||      
johnk at spasm.niddk.nih.gov          ||  /  /||  ||
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that's MISTER protein G to you!     |/__/|      |
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My parents went to Zaire and all I got 
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