2nd Annual Japanese COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

James W. Larkin jamesl at healthtech.com
Tue Oct 7 10:33:10 EST 1997


2nd Annual Japanese 
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
October 29-31, 1997  Keio Plaza Inter-Continental,Tokyo, Japan
Corporate Sponsor: Tripos Corp.
Corporate Support: Trega Biosciences
                   Oxford Asymmetry
                   Arqule, Inc

On Wednesday, October 29, there will be a series of Corporate 
Partnering presentations. Material from each of the presenting 
companies will be posted on the Cambridge Healthtech Web page, to 
allow for review by attendees prior to the meeting. Invitations 
will be extended to a number of pharmaceutical executives throughout 
Japan and elsewhere in Asia to attend this portion of the meeting on 
a complimentary basis. At the end of the partnering session, the 
exhibits will be available for viewing as well.

Initial Partnering Presentations
        Arris Pharmaceuticals                   Oxford Asymmetry
        Aurora Biosciences                      Trega Biosciences
        IRORI Quantum Microchemistry            Tripos Corporation
        Oncogene Science, Inc.                  Versicor
        Orchid BioComputer, Inc.

LIBRARIES
APPLICATIONS OF COMBINATORIAL CHEMISTRY TO DRUG DISCOVERY IN 
INFECTIOUS DISEASE
        Dr. Eric M. Gordon, Versicor
LOW-DIVERSITY SMART LIBRARYTM TECHNOLOGY: LIBRARIES FOR THE 
DEVELOPMENT OF SMALL MOLECULE
        Dr. Michael Kahn, Molecumetics, Ltd.
THE DESIGN OF A UNIVERSAL INFORMER LIBRARY FOR DRUG DISCOVERY
        Dr. Peter Myers, CombiChem, Inc.
COMBINATORIAL CHEMISTRY: FROM CONCEPT TO APPLICATION AS A DRUG 
DISCOVERY TOOL
        Dr. Alex Polinsky, Alanex Corporation
COMBINATORIAL ORGANIC SYNTHESIS USING RADIO FREQUENCY MEMORY DEVICES
        Dr. Anthony Czarnik, IRORI Quantum Microchemistry
MICROFABRICATION FOR MICROCHEMISTRY IN HIGH-THROUGHPUT DRUG DISCOVERY
        Dr. Pat Conway, Orchid BioComputer, Inc.
TITLE TO BE ANNOUNCED
        Dr. David Casebier, ArQule, Inc.

COMBINATORIAL SYNTHESIS
DEVELOPMENT OF SYNTHETIC TOOLS FOR PREPARATION OF SMALL MOLECULE 
LIBRARIES
        Dr. Tony Baxter, Oxford Asymmetry
ADVANCES IN METHODOLOGY FOR HIGH-THROUGHPUT SOLUTION AND SOLID-PHASE 
SYNTHESIS OF SMALL MOLECULES
        Dr. Douglas Livingston, Arris Pharmaceutical Corporation
SYNTHESIS OF HETEROCYCLES ON THE SOLID PHASE
        Dr. Michael J. Green, Trega Biosciences
TITLE TO BE ANNOUNCED
        Dr. Alasdair MacDonald, Argonaut Technologies, Inc.
ROBOTICS AND SMALL-SIZED CHEMISTRY FOR COMBINATORIAL REACTION AUTOMATION
        Dr. Akito Tanaka, Fujisawa Pharmaceuticals (tentative)
TITLE TO BE ANNOUNCED
        Advanced ChemTech (invited)

INFORMATICS
OPTIVERSE™ AND CHEMSPACE™: AN INTEGRATED STRATEGY FOR DESIGN AND 
SYNTHESIS OF LEAD DISCOVERY AND LEAD REFINEMENT LIBRARIES USING A 
NOVEL VIRTUAL LIBRARY TECHNOLOGY
        Dr. Peter Hecht, Tripos GmbH, Munich
TITLE TO BE ANNOUNCED
        Dr. Barry Robson, MDL Information Systems (invited)
NOVEL SOFTWARE TOOLS FOR CHEMICAL DIVERSITY AND COMBINATORIAL CHEMISTRY
        Dr. Robert Pearlman, University of Texas, Austin

SCREENING
AUTOMATED HTS AT AMGEN: AN OVERVIEW OF WORKSTATIONS AND INTEGRATED 
SYSTEMS APPROACHES
        Dr. Jason Armstrong, Amgen
NOVEL FLUOROGENIC BIOASSAY TECHNOLOGY FOR RAPID SCREEN DEVELOPMENT FOR 
ULTRA HIGH-THROUGHPUT SCREENING
        Dr. Harry Stylli, Aurora Biosciences
STRATEGIC LEVERAGING OF AN ESTABLISHED DRUG DISCOVERY ENGINE
        Dr. Mel Reichman, Oncogene Science, Inc.
TITLE TO BE ANNOUNCED
        Dr. Shina Tanaka, Nihon Millipore (tentative)
TITLE TO BE ANNOUNCED
        Dr. Kurt Schilling, Molecular Devices (invited)

Cambridge Healthtech is pleased to again work closely with the Japan 
Combinatorial Chemistry Focus Group (J.C.C.F.) for this second annual 
meeting. Prior to the opening of the technical meeting there will be a 
tutorial workshop, offered in Japanese, for review of technical terms 
and concepts that will be covered during the meeting. There will also 
be a series of Corporate Partnering Presentations, to which leading 
decision makers from Asian pharmaceutical companies will be invited. 
The technical program will first focus on develop-ments in the design 
and synthesis of small molecule combinatorial libraries for lead 
identification and lead optimization. Advances in high throughput 
screening, including automation, novel assays, data handling, and 
interpretation, as well as integration of these issues, will then be 
featured. Thirty exhibitors participated in the trade exhibit last 
year, and more are expected to take advantage of this unique 
opportunity to be in touch with key researchers and managers attending 
this meeting. Interest and application of these two key technologies 
are expected to follow a similar pattern of rapid growth as is being 
experienced elsewhere throughout the world.

INITIAL EXHIBITORS
        AMERSHAM KK                     NALGE NUNC
        ARGONAUT TECHNOLOGIES           NIHON MILLIPORE
        BECKMAN INSTRUMENTS             OXFORD ASYMMETRY
           (JAPAN) LTD.                 ROBBINS SCIENTIFIC
        CEREP                           TECAN CO.
        CONTACT SERVICE CO.             TEIJIN SYSTEMS
        CORNING COSTAR CORP.            TOYOBO
        DAIICHI PURE CHEMICALS          TRIPOS CORP.
        M & S INSTRUMENTS               WHATMAN POLYFILTRONICS
        MATRIX TECHNOLOGIES

CALL FOR EXHIBITORS
Space is available for organizations interested in exhibiting 
technologyor services to reach the targeted audience that will be 
attending this meeting on Combinatorial Chemistry & High Throughput 
Screening. Please contact Jim MacNeil of Cambridge Healthtech 
Institute at 617-630-1341 to obtain an exhibitor package or to inquire 
about offering a workshop during the meeting. Exhibit space is 
limited so call now to reserve a space at this premier event.

HOTEL INFORMATION
Keio Plaza Inter-Continental     Room reservations must be made 
2-1, Nishi-Shinjuku 2-Chome      through Cambridge Healthtech  
Shinjuku-ku, Tokyo 160 JAPAN     Institute (CHI). You must fill out 
                                 the reservation form and send it 
T: 81-3-3344-0111                back to CHI by Sept. 12, 1997
F: 81-3-3345-8269                (reservation forms may not be  
                                 accepted after this date and will  
Cut-off Date:September 12, 1997  be subject to hotel reservation 
                                 policies). Limited rooms are a
Room Rate: 18,000 JPY-Single     vailable and are subject to  
           20,000 JPY-Double     availability. Please call CHI with 
                                 any questions, e-mail Jennifer Katz 
                                 at jkatz at healthtech.com, or contact 
                                 us by fax at 617-630-1325.

TRAVEL INFORMATION
TRAVELWORLD             T: 717-288-9311 or 800-828-6033
601 Market Street       F: 717-288-4693
Kingston, PA 18704

Exclusive airline discounts are available on specific airlines when 
tickets are purchased through Travelworld at least 14 days prior to 
the meeting date. Some restrictions apply.

Handicapped Equal Access:  In accordance with the ADA, Cambridge 
Healthtech Institute is pleased to arrange for special accommodations 
for attendees with special needs.  All request for such assistance 
must be submitted in writing to CHI at least 30 days prior to the 
start of the meeting.

Each registration includes all conference sessions, posters and 
exhibits, one luncheon and reception, continental breakfasts, all 
refreshment breaks, and a copy of the document binder. 

A group rate is available for three or more people from the same 
organization.  Call for more details.

SUBSTITUTION CANCELLATION POLICY

In the event that you need to cancel a registration you may:
   Transfer your registration to a colleague within your organization.
   Credit your registration to another Cambridge Healthtech Institute 
   program.
   Request a refund minus a $75 processing fee.
   Request a refund minus the cost ($195) of ordering a copy of 
   the document binder.

Cancellations will only be accepted up to one week prior to the 
conference.

Program and speakers are subject to change.

--------------------CUT AND PRINT HERE-----------------------------

YES |__| Please register me for:                   E-Mail #568E-J70
         Combinatorial Chemistry & High Throughput Screening

On-site or Late Registration (after September 12, 1997)
        $995 |__| Commercial 
        $495 |__| Academic, Government, Hospital-Affiliated

|__| Complimentary Registration for Partnering Presentations ONLY

FIRST NAME:______________________________________________________

LAST NAME:_______________________________________________________

TITLE:___________________________________________________________

DIV./DEPT.:______________________________________________________

COMPANY:_________________________________________________________

ADDRESS:_________________________________________________________

City/State/ZIP:__________________________________________________

COUNTRY:_________________________________________________________

TELEPHONE:____________________________ Fax:______________________

E-MAIL:__________________________________________________________

|__| Please send information on exhibiting and opportunities to 
     present workshops.
|__| Enclosed is a check or money order payable to Cambridge 
     Healthtech Institute, drawn on a U.S. bank, in U.S. currency.

|__| Please charge: |__| AMEX (15 digits) |__| Visa (13 to 16 digits)
                    |__| MasterCard (16 digits)

Card #:___________________________________________________________

Exp. Date:________________________________________________________

Cardholder's Name:________________________________________________

Signature:________________________________________________________

Cardholder's Address (if different from above):___________________

__________________________________________________________________

|__| Reserve with credit card information listed above and invoice 
     me. (Invoices must be paid in full by the deadline to retain 
     registration discount.  Invoices unpaid one week prior to 
     conference will be billed to credit card at full registration 
     rate.)

If you plan to register on site, please check with CHI beforehand 
for space availability.

KEIO PLAZA INTER-CONTINENTAL RESERVATION FORM 
(only valid until September 12, 1997)
* SIGNATURE:_______________________________________________________
(Authorizes agreement to the terms under Hotel Information; please 
note your reservation form will not be processed without signature.)
Hotel arrival date:_____ / _____  Hotel departure date:_____ / ___
                   Month / Day                         Month / Day
Special Requests (subject to availability):________________________

___________________________________________________________________

|__| Credit Card to Guarantee Reservation:
        |__| AMEX (15 digits)           |__| Visa (13 to 16 digits)
        |__| MasterCard (16 digits)
        |__| Use above credit card information.

Reservations WILL NOT be accepted without a credit card guarantee.

CARD #:_____________________________________ EXP. DATE:_________________
CARDHOLDER’S NAME: _________________________ SIGNATURE:_________________

FAX or MAIL your reservation/registration to: 
Cambridge Healthtech Institute
1037 Chestnut Street
Newton Upper Falls, MA 02164
tel: 617-630-1300
fax: 617-630-1325
e-mail: chi at healthtech.com
http:www.healthtech.com/conferences/





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