Structural Biology Postdocs, Galveston, TX, USA

Stan Watowich watowich at
Wed Oct 22 18:44:17 EST 1997

Postdoctoral Positions in 
Structural Biology and Signal Transduction

Two postdoctoral positions are available to (1) study the structural 
aspects of growth factor receptor activation and (2) develop inhibitors 
of growth factor receptor activation. Our laboratory has developed novel 
soluble molecules that mimic the active state of growth factor receptors. 
These soluble receptor mimics are being used in crystallographic and 
biochemical studies, and as targets to screen combinatorial libraries 
for inhibitors of receptor activation.

Candidates must have research experience in either X-ray crystallography, 
molecular biology, protein biochemistry or combinatorial chemistry.

Facilities include state-of-the-art laboratories for X-ray
cryocrystallography, large-scale bacterial cell growth, Sf9 insect cell
growth, tissue culture 
and protein analysis. Instrumentation available for structural studies 
include a MacScience 30 cm imaging plate detector, a Siemens 2K CCD
detector, two rotating anode X-ray generators equipped with cross-coupled 
Gobel mirrors, a Micromass ion-spray mass spectrometer, SGI multiprocessor 
computers and graphics workstations, and a Cray J90 supercomputer. 

Applicants should send a CV, list of publications, statement of research
interests, and the names, addresses and telephone numbers of three 
references to: 

Dr. Stan Watowich
Sealy Center for Structural Biology
Department of Human Biological Chemistry & Genetics
University of Texas Medical Branch
Galveston, TX 77555-0645
Phone: 409-747-4749
Fax: 409-747-4745
E-mail:watowich at 

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